Pyogenic liver abscess medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Treatment

Treatment of pyogenic liver abscess include:[1]

 
 
 
 
 
Treatment
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Non-surgical treatment
 
 
 
Open surgical drainage
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Conservative management with antibiotics alone
 
Percutaneous drainage

Medical Therapy

Empiric antibiotic therapy based on culture and sensitivity include

First choice

  • 1.Monotherapy
  • 2.Combination therapy
  • Preferred regimen(1):Ceftriaxone 1 g IV every 24 hours or 2 g IV every 12 hours for CNS infection plus Metronidazole 500 mg IV every eight hours

Alternative Emperic Regimens

  • 2.Monotherapy
  • Preferred regimen(1):Imipenem-cilastatin 500 mg IV every six hours
  • Preferred regimen(2):Meropenem 1 g IV every eight hours
  • Preferred regimen(3):Doripenem 500 mg IV every eight hours
  • Preferred regimen(4):Ertapenem 1 g IV once daily

References

  1. Malik AA, Bari SU, Rouf KA, Wani KA (2010). "Pyogenic liver abscess: Changing patterns in approach". World J Gastrointest Surg. 2 (12): 395–401. doi:10.4240/wjgs.v2.i12.395. PMC 3014521. PMID 21206721.