Psoriasis history and symptoms

Revision as of 18:24, 15 June 2017 by Skazmi (talk | contribs)
Jump to navigation Jump to search

Psoriasis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Psoriasis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X-ray

Ultrasound

CT scan

MRI

Other Imaging Studies

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Psoriasis history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Psoriasis history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Psoriasis history and symptoms

CDC on Psoriasis history and symptoms

Psoriasis history and symptoms in the news

Blogs on Psoriasis history and symptoms

Directions to Hospitals Treating Psoriasis

Risk calculators and risk factors for Psoriasis history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

History

Age of onset[1]

  • Psoriasis can first appear at any age; however, a bimodal distribution of the age of onset is usually seen.
  • The first peak for the development of psoriasis occurs between 20 years to 35 years and the second peak is between 40 years to 65 years of life.

Family History[2]

  • Patients with early disease onset often have a positive family history of psoriasis, frequent association with histocompatibility antigen (HLA)- Cw6, and more severe disease. Those with onset after the age of 40 usually have a negative family history and a normal frequency of the HLA- Cw6 allele.

Initial Presentation

  • A typical patient of psoriasis will present with a history of a long-term erythematous scaly area with ocular and joint involvement depending upon the clinical subtype and chronicity of the disease. There may be multiple relapses and remissions.

Past Medical History[3]

  • Past medical history of the patient may include viral or bacterial infection, diabetes, hypertension, chronic kidney disease and/or obesity due to association of psoriasis with these conditions.

Social History[4]

  • Social history of the patient may indicate smoking, excessive alcohol consumption and/or a recent stressful event if life associated with an acute exacerbation of psoriasis.

Symptoms

Common Symptoms[5]

Common symptoms of psoriasis may include the following:

  • A long-term history of erythematous scaly area, which may involve multiple areas of the body.
  • Sudden onset of many small areas of scaly redness.
  • Recent streptococcal throat infection, viral infection, immunization, use of antimalarial drug, or trauma.
  • Pain, which has been described by patients as unpleasant, superficial, sensitive, itchy, hot or burning  (especially in erythrodermic psoriasis and in some cases of traumatized plaques or in the joints affected by psoriatic arthritis).
  • Pruritus (especially in eruptive, guttate psoriasis).
  • High fever in erythrodermic and pustular psoriasis.
  • Dystrophic nails.
  • Long-term rash with recent presentation of arthralgia.
  • Arthralgia without any visible skin findings.
  • Ocular symptoms include redness and tearing due to conjunctivitis or blepharitis.
  • Avoidance of situations requiring social interaction.

Less Common Symptoms[6][7]

  • Enthesitis
  • Depression leading to:
    • Insomnia
    • Decreased appetite
    • Guilt
    • Loss of energy
    • Decreased concentration
  • Dactylitis
  • Geographic tongue ( The dorsal surface may have sharply demarcated gyrate red patches with a white to yellow border that may evolve giving the appearence of a map)

References

  1. Swanbeck G, Inerot A, Martinsson T, Wahlström J, Enerbäck C, Enlund F, Yhr M (1995). "Age at onset and different types of psoriasis". Br. J. Dermatol. 133 (5): 768–73. PMID 8555031.
  2. Naldi L, Parazzini F, Brevi A, Peserico A, Veller Fornasa C, Grosso G, Rossi E, Marinaro P, Polenghi MM, Finzi A (1992). "Family history, smoking habits, alcohol consumption and risk of psoriasis". Br. J. Dermatol. 127 (3): 212–7. PMID 1390163.
  3. Ni C, Chiu MW (2014). "Psoriasis and comorbidities: links and risks". Clin Cosmet Investig Dermatol. 7: 119–32. doi:10.2147/CCID.S44843. PMC 4000177. PMID 24790463.
  4. Naldi L, Parazzini F, Brevi A, Peserico A, Veller Fornasa C, Grosso G, Rossi E, Marinaro P, Polenghi MM, Finzi A (1992). "Family history, smoking habits, alcohol consumption and risk of psoriasis". Br. J. Dermatol. 127 (3): 212–7. PMID 1390163.
  5. Ljosaa TM, Rustoen T, Mörk C, Stubhaug A, Miaskowski C, Paul SM, Wahl AK (2010). "Skin pain and discomfort in psoriasis: an exploratory study of symptom prevalence and characteristics". Acta Derm. Venereol. 90 (1): 39–45. doi:10.2340/00015555-0764. PMID 20107724.
  6. "Psoriasis: epidemiology, natural history, and differential diagnosis | PTT".
  7. Kurd SK, Troxel AB, Crits-Christoph P, Gelfand JM (2010). "The risk of depression, anxiety, and suicidality in patients with psoriasis: a population-based cohort study". Arch Dermatol. 146 (8): 891–5. doi:10.1001/archdermatol.2010.186. PMC 2928071. PMID 20713823.

Template:WH Template:WS