Prolactinoma causes: Difference between revisions

Jump to navigation Jump to search
m (Bot: Removing from Primary care)
 
(18 intermediate revisions by 7 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Prolactinoma}}
{{Prolactinoma}}
{{CMG}} {{AE}}{{Faizan}}
{{CMG}};{{AE}} {{Anmol}}, {{Faizan}}
 
==Overview==
==Overview==
There are no established causes for prolactinoma. Most [[pituitary]] tumors are sporadic.
There are no established causes of [[prolactinoma]]. Most cases of [[prolactinoma]] are sporadic. [[Prolactinoma]] may occur in approximately 30% of [[multiple endocrine neoplasia type 1]] patients. It may also occur with [[Carney complex]] or [[McCune-Albright syndrome]].


==Causes==
==Causes==
There are no established causes for prolactinoma. Most pituitary tumors are sporadic. A minority of prolactinomas are associated with [[familial]] syndromes.


===Familial Causes===
===Common causes===
*Sporadic
*[[Hereditary]] causes:
**[[Multiple endocrine neoplasia type 1]] ([[MEN 1]])


[[Prolactinoma]] may occur as part of a hereditary disorder called [[multiple endocrine neoplasia type 1]] ([[MEN 1]]). A minority of prolactinomas are associated with:<ref>http://radiopaedia.org/articles/pituitary-adenoma</ref>
===Less common/rare causes===
*[[Multiple endocrine neoplasia type 1]] ([[MEN I]])
*[[Hereditary]] causes:
*[[Carney complex]]
**A minority of [[prolactinoma]] are associated with:<ref name="pmid16411062">{{cite journal| author=Ciccarelli A, Daly AF, Beckers A| title=The epidemiology of prolactinomas. | journal=Pituitary | year= 2005 | volume= 8 | issue= 1 | pages= 3-6 | pmid=16411062 | doi=10.1007/s11102-005-5079-0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16411062  }} </ref><ref name="pmid17613551">{{cite journal| author=Karhu A, Aaltonen LA| title=Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update. | journal=Hum Mol Genet | year= 2007 | volume= 16 Spec No 1 | issue=  | pages= R73-9 | pmid=17613551 | doi=10.1093/hmg/ddm036 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17613551  }} </ref>
*[[McCune-Albright Syndrome]]
**#[[Carney complex]]
*MEN like syndrome (CKDN1B loss of function)
**#[[McCune-Albright Syndrome]]
 
**#Isolated [[familial]] [[pituitary adenoma]]
=== Other Causes ===
**#MEN1-like syndrome
Other causes include:
*The xenoestrogenic chemical Bisphenol-A has been shown to lead to [[hyperprolactinaemia]] and growth of prolactin-producing pituitary cells.<ref>^ Goloubkova T, Ribeiro MF, Rodrigues LP, Cecconello AL, Spritzer PM (April 2000). "Effects of xenoestrogen bisphenol A on uterine and pituitary weight, serum prolactin levels and immunoreactive prolactin cells in ovariectomized Wistar rats". Arch. Toxicol. 74 (2): 92–8. doi:10.1007/s002040050658. PMID 10839476</ref> The increasing and prolonged exposure of Bisphenol-A from childhood may contribute to the growth of a [[prolactinoma]].


== References ==
== References ==
Line 24: Line 25:
{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}
[[Category:Disease]]
[[Category:Disease]]
[[Category:Neuroendocrinology]]
[[Category:Neuroendocrinology]]
[[Category:Mature chapter]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Endocrinology]]
[[Category:Up-To-Date]]
[[Category:Neurology]]
[[Category:Neurosurgery]]

Latest revision as of 23:49, 29 July 2020

Prolactinoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Prolactinoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

ECG

X-ray

Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Prolactinoma causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Prolactinoma causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Prolactinoma causes

CDC on Prolactinoma causes

Prolactinoma causes in the news

Blogs on Prolactinoma causes

Directions to Hospitals Treating Prolactinoma

Risk calculators and risk factors for Prolactinoma causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2], Faizan Sheraz, M.D. [3]

Overview

There are no established causes of prolactinoma. Most cases of prolactinoma are sporadic. Prolactinoma may occur in approximately 30% of multiple endocrine neoplasia type 1 patients. It may also occur with Carney complex or McCune-Albright syndrome.

Causes

Common causes

Less common/rare causes

References

  1. Ciccarelli A, Daly AF, Beckers A (2005). "The epidemiology of prolactinomas". Pituitary. 8 (1): 3–6. doi:10.1007/s11102-005-5079-0. PMID 16411062.
  2. Karhu A, Aaltonen LA (2007). "Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update". Hum Mol Genet. 16 Spec No 1: R73–9. doi:10.1093/hmg/ddm036. PMID 17613551.

Template:WikiDoc Sources