Pneumoconiosis differential diagnosis: Difference between revisions
Jump to navigation
Jump to search
| Line 41: | Line 41: | ||
|↑ FEV1/FVC | |↑ FEV1/FVC | ||
|Wheezing, rhonchi, crackles | |Wheezing, rhonchi, crackles | ||
| | | + | ||
| | | | ||
| | | | ||
| Line 54: | Line 54: | ||
| style="background: #F5F5F5; padding: 5px;" |Wheezing, crackles | | style="background: #F5F5F5; padding: 5px;" |Wheezing, crackles | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Normal | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Normal | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Mass lesion, hilar lymphadenopathy | ||
| style="background: #F5F5F5; padding: 5px;" |Bronchoscopy | | style="background: #F5F5F5; padding: 5px;" |Bronchoscopy | ||
|- | |- | ||
| Line 66: | Line 66: | ||
| style="background: #F5F5F5; padding: 5px;" |Wheezing, rhonchi, crackles | | style="background: #F5F5F5; padding: 5px;" |Wheezing, rhonchi, crackles | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |↑WBC | ||
| style="background: #F5F5F5; padding: 5px;" |↓O2, ↑CO2 | | style="background: #F5F5F5; padding: 5px;" |↓O2, ↑CO2 | ||
| style="background: #F5F5F5; padding: 5px;" |Patchy consolidation, nodular opacities | | style="background: #F5F5F5; padding: 5px;" |Patchy consolidation, nodular opacities | ||
| Line 78: | Line 78: | ||
| style="background: #F5F5F5; padding: 5px;" |Wheezing | | style="background: #F5F5F5; padding: 5px;" |Wheezing | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Normal | ||
| style="background: #F5F5F5; padding: 5px;" |Respiratory alkalosis, Metabolic acidosis | | style="background: #F5F5F5; padding: 5px;" |Respiratory alkalosis, Metabolic acidosis | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Flat diaphragm | ||
| style="background: #F5F5F5; padding: 5px;" |Physical exam, spirometry | | style="background: #F5F5F5; padding: 5px;" |Physical exam, spirometry | ||
|- | |- | ||
| Line 89: | Line 89: | ||
| style="background: #F5F5F5; padding: 5px;" |↓ FEV1/FVC | | style="background: #F5F5F5; padding: 5px;" |↓ FEV1/FVC | ||
| style="background: #F5F5F5; padding: 5px;" |Wheezing | | style="background: #F5F5F5; padding: 5px;" |Wheezing | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | + | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |↑ Eosinophil | ||
| style="background: #F5F5F5; padding: 5px;" |Respiratory alkalosis, Metabolic acidosis | | style="background: #F5F5F5; padding: 5px;" |Respiratory alkalosis, Metabolic acidosis | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Normal | ||
| style="background: #F5F5F5; padding: 5px;" |Physical exam, spirometry before and after brondchodilator | | style="background: #F5F5F5; padding: 5px;" |Physical exam, spirometry before and after brondchodilator | ||
|- | |- | ||
| Line 102: | Line 102: | ||
| style="background: #F5F5F5; padding: 5px;" |Wheezing, rhonchi, crackles | | style="background: #F5F5F5; padding: 5px;" |Wheezing, rhonchi, crackles | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Normal | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |↓O2, ↑CO2 | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Peripheral pulmonary infiltrative opacification | ||
| style="background: #F5F5F5; padding: 5px;" |HRCT | | style="background: #F5F5F5; padding: 5px;" |HRCT | ||
|- | |- | ||
| Line 114: | Line 114: | ||
| style="background: #F5F5F5; padding: 5px;" |Crackles | | style="background: #F5F5F5; padding: 5px;" |Crackles | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Normal | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |↓O2, ↑CO2 | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Hilar adenopathy | ||
| style="background: #F5F5F5; padding: 5px;" |HRCT | | style="background: #F5F5F5; padding: 5px;" |HRCT | ||
|- | |- | ||
| Line 126: | Line 126: | ||
| style="background: #F5F5F5; padding: 5px;" |Wheezing, rhonchi, crackles | | style="background: #F5F5F5; padding: 5px;" |Wheezing, rhonchi, crackles | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |↑WBC, neutrophilia | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Normal | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Lobar consolidation | ||
| style="background: #F5F5F5; padding: 5px;" |CXR, CT Scan | | style="background: #F5F5F5; padding: 5px;" |CXR, CT Scan | ||
|} | |} | ||
Revision as of 21:09, 30 April 2021
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dushka Riaz, MD
Overview
Pneumoconiosis must be differentiated from other diseases that cause chronic cough and dyspnea.
Differentiating Pneumoconiosis from other Diseases
Pneumoconiosis must be differentiated from other diseases that cause cough and dyspnea.
Differentiating pneumoconiosis from other diseases on the basis of dyspnea and cough
On the basis of cough and chronic dyspnea, pneumoconiosis must be differentiated from lung malignancy, tuberculosis, emphysema, asthma, interstitial lung disease, pneumonia, and sarcoidosis.
| Diseases | Clinical manifestations | Para-clinical findings | Gold standard | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms | Physical examination | |||||||||
| Lab Findings | Imaging | |||||||||
| Chronic Dyspnea | Cough | Fever | Spirometry | Auscultation | Tachypnea | CBC | ABG | Imaging | ||
| Pneumoconiosis | + | + | + | ↑ FEV1/FVC | Wheezing, rhonchi, crackles | + | HRCT | |||
| Lung Malignancy | + | + | - | ↓Vt, ↑RV | Wheezing, crackles | Normal | Normal | Mass lesion, hilar lymphadenopathy | Bronchoscopy | |
| Tuberculosis | + | + | + | Restrictive, obstructive, or mixed | Wheezing, rhonchi, crackles | ↑WBC | ↓O2, ↑CO2 | Patchy consolidation, nodular opacities | IFN-y assay and acid fast stain | |
| Emphysema | + | + | - | ↓ FEV1/FVC | Wheezing | Normal | Respiratory alkalosis, Metabolic acidosis | Flat diaphragm | Physical exam, spirometry | |
| Asthma | + | + | - | ↓ FEV1/FVC | Wheezing | + | ↑ Eosinophil | Respiratory alkalosis, Metabolic acidosis | Normal | Physical exam, spirometry before and after brondchodilator |
| Interstitial lung diseases | + | + | - | ↑ FEV1/FVC | Wheezing, rhonchi, crackles | Normal | ↓O2, ↑CO2 | Peripheral pulmonary infiltrative opacification | HRCT | |
| Sarcoidosis | + | + | - | ↑ FEV1/FVC | Crackles | Normal | ↓O2, ↑CO2 | Hilar adenopathy | HRCT | |
| Pneumonia | + | + | + | Normal | Wheezing, rhonchi, crackles | ↑WBC, neutrophilia | Normal | Lobar consolidation | CXR, CT Scan | |