Patent foramen ovale historical perspective

Patent Foramen Ovale Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]

Overview

Leonardi Botali (1564), was the first to describe the presence of foramen ovale at birth. In 1877, Conheim first described a cryptogenic stroke with patent foramen ovale.