Pancreatic cancer screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]

Overview

In the general population, screening of large groups is not currently considered effective, although newer techniques, and the screening of tightly targeted groups, are being evaluated.[1][2] Nevertheless, regular screening with endoscopic ultrasound and MRI/CT imaging is recommended for pancreatic cancer in high risk individuals.

Screening

  • In the general population, screening of large groups is not currently considered effective, although newer techniques, and the screening of tightly targeted groups, are being evaluated.[1][2] Nevertheless, regular screening with endoscopic ultrasound and MRI/CT imaging is recommended for pancreatic cancer in high risk individuals.
  • Individuals with the following conditions are also at an increased risk of pancreatic cancer:[3]
    • Hereditary pancreatitis
    • Familial pancreatic cancer
    • Peutz-Jeghers disease
    • Familial atypical mole melanoma syndrome (FAMMM)
    • Cystic fibrosis of pancreas,
    • Familial cancer syndromes such as:
      • Lynch syndrome
      • Familial adenomatous polyposis (FAP)
      • von Hippel-Lindau syndrome
      • Multiple endocrine neoplasia type 1
      • Hereditary breast and ovarian cancer-BRCA1 and BRCA2 mutations

References

  1. 1.0 1.1 He XY, Yuan YZ (August 2014). "Advances in pancreatic cancer research: moving towards early detection". World J. Gastroenterol. 20 (32): 11241–8. doi:10.3748/wjg.v20.i32.11241. PMC 4145762. PMID 25170208.
  2. 2.0 2.1 Okano K, Suzuki Y (August 2014). "Strategies for early detection of resectable pancreatic cancer". World J. Gastroenterol. 20 (32): 11230–40. doi:10.3748/wjg.v20.i32.11230. PMC 4145761. PMID 25170207.
  3. Goral V (2015). "Pancreatic Cancer: Pathogenesis and Diagnosis". Asian Pac J Cancer Prev. 16 (14): 5619–24. PMID 26320426.