Pancreatic cancer epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
In the United States, the age-adjusted prevalence of invasive pancreatic cancer is 11.7 per 100,000 in 2011. Pancreatic cancer is more prevalent in males than females.
Epidemiology and Demographics
Prevalence
- In the United States, the age-adjusted prevalence of invasive pancreatic cancer is 11.7 per 100,000 in 2011.[1]
Mortality rate
- As per the GLOBOCAN 2012 estimates, pancreatic cancer leads to more than 331,000 deaths per year (accounting for 4.0% of all deaths), making it as the seventh leading cause of cancer death in both males and females. [2]
- In 2012, about 338,000 suffered from pancreatic cancer, making it the 11th most common cancer.[2] [3]
Incidence
- Estimated new cases and deaths from pancreatic cancer in the United States in 2015:
- New cases: 48,960
- Deaths: 40,560
- The incidence of carcinoma of the pancreas has markedly increased over the past several decades and ranks as the fourth leading cause of cancer death in the United States.
- Incidence rates for pancreatic cancer in 2012 were: [2]
- In United States, the highest incidence rate of 7.4 per 100,000 people
- In Western Europe, 7.3 per 100,000 people
- In Europe and Australia/New Zealand, equally about 6.5 per 100,000 people
- In Middle Africa and South-Central Asia, the lowest incidence rate of 1.0 per 100,000 people
- In Pakistan, 0.5 per 100,000 people
- The delay-adjusted incidence of invasive pancreatic cancer in 2011 was estimated to be 12.63 per 100,000 persons in the United States[1]
- In 2011, the age-adjusted incidence of invasive pancreatic cancer was 12.30 per 100,000 persons in the United States[1]
Age
- While the overall age-adjusted incidence of invasive pancreatic cancer in the United States between 2007 and 2011 is 12.3 per 100,000, the age-adjusted incidence of invasive pancreatic cancer by age category is:[1]
- Under 65 years: 4 per 100,000
- 65 and over: 69.4 per 100,000
Gender
- In the United States, the age-adjusted prevalence of invasive pancreatic cancer by gender in 2011 is:[1]
- In males: 12.3 per 100,000
- In females: 11.2 per 100,000
- In the United States, the delay-adjusted incidence of invasive pancreatic cancer by gender in 2011 is:[1]
- In males: 14.75 per 100,000 persons
- In females: 10.93 per 100,000 persons
- In the United States, the age-adjusted incidence of invasive pancreatic cancer by gender on 2011 is:[1]
- In males: 14.38 per 100,000 persons
- In females: 10.62 per 100,000 persons
Shown below is an image depicting the delay-adjusted incidence and observed incidence of invasive pancreatic cancer by gender and race in the United States between 1975 and 2011. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.[1]
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Race
- Shown below is a table depicting the age-adjusted prevalence of invasive pancreatic cancer by race in 2011 in the United States.[1]
| All Races | White | Black | Asian/Pacific Islander | Hispanic | |
| Age-adjusted prevalence | 11.7 per 100,000 | 11.7 per 100,000 | 13 per 100,000 | 10.4 per 100,000 | 9.6 per 100,000 |
Shown below is an image depicting the incidence of invasive pancreatic cancer by race in the United States between 1975 and 2011.[1]
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API: Asian/Pacific Islander; AI/AN: American Indian/ Alaska Native
Percent Distribution of Invasive Pancreatic Cancer by Histology
Among patients with histologically confirmed cases of invasive pancreatic cancer, the percent distribution of the types of the disease in the United States are:[1]
- Carcinoma: 97.9%
- Epidermoid carcinoma: 0.2%
- Adenocarcinoma: 86%
- Adenocarcinoma not otherwise specified: 69.9%
- Papillary adenocarcinoma: 0.1%
- Mucinous adenocarcinoma: 2.6%
- Mucin- producing adenocarcinoma: 1.1%
- Inflitrating duct carcinoma: 9.8%
- Other adenocarcinoma: 2.6%
- Other specific carcinoma: 6.5%
- Carcinoma not otherwise specified: 5.2%
- Sarcoma and other soft tissue tumors: 0.1%
- Other specific types: 0.1%
- Unspecified: 1.9%
Developed Countries
- Developed countries have the highest incidence and mortality rates of pancreatic cancer. [2]
Developing Countries
- Pancreatic cancer incidence and mortality varies across different countries. The incidence is considerably lower in developing countries. [2]
Awareness
- November is pancreatic cancer awareness month.
- Purple is the traditional color chosen to represent pancreatic cancer awareness.
- The National Cancer Institute’s cancer research budget was $4.824 billion in 2004, an estimated $52.7 million of which was devoted to pancreatic cancer.[4]
- Research spending per pancreatic cancer patient is $1145, the lowest of any leading cancer.[5]
- The Pancreatic Cancer Action Network (PanCAN) was created as an advocacy group for pancreatic cancer.
- The National Charity pancreatic cancer UK works to raise awareness in the UK.
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.
- ↑ 2.0 2.1 2.2 2.3 2.4 Ilic M, Ilic I (2016). "Epidemiology of pancreatic cancer". World J Gastroenterol. 22 (44): 9694–9705. doi:10.3748/wjg.v22.i44.9694. PMC 5124974. PMID 27956793.
- ↑ Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M; et al. (2015). "Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012". Int J Cancer. 136 (5): E359–86. doi:10.1002/ijc.29210. PMID 25220842.
- ↑ http://pancan.org/About/pancreaticCancerStats.html
- ↑ http://pancan.org/About/pancreaticCancerStats.html