Pancreatic cancer CT: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Pancreatic cancer}} | {{Pancreatic cancer}} | ||
{{CMG}}; | {{CMG}}; {{AE}} {{ARK}} | ||
==Overview== | ==Overview== | ||
Findings on [[Computed tomography|CT scan]] that may be suggestive of [[pancreatic cancer]] include [[Morphology|morphological]] changes of the [[gland]], destruction of the peripancreatic fat and loss of the sharp margins with surrounding structures, involvement of the regional [[Lymph node|lymph nodes]] and adjacent [[Circulatory system|vasculature]], [[Pancreatic duct|pancreatic ductal]] [[Dilation|dilatation]], [[Pancreas|pancreatic]] atrophy and [[obstruction]] of the [[common bile duct]] . [[Computed tomography|MDCT (Multi-detector row computed tomography)]] the [[imaging]] modality widely used in suspected [[pancreatic cancer]] patients as the pre-operative examination. [[Computed tomography|MDCT]] is used as the primary [[imaging]] modality, and is used in conjunction with [[Positron emission tomography|PET]]/[[Computed tomography|CT]]. [[Computed tomography|MDCT]] helps in local and distant disease assessment in a single scan. [[Computed tomography|MDCT]] is useful in the evaluation of [[vascular]] involvement, which helps in predicting the [[tumor]] resectability. | |||
==CT== | ==CT== | ||
===Pancreatic Adenocarcinoma=== | ===Pancreatic Adenocarcinoma=== | ||
*[[Computed tomography|MDCT (Multi-detector row computed tomography]]) the [[imaging]] modality widely used in suspected [[pancreatic cancer]] patients as the pre-operative examination. <ref name="pmid24976723">{{cite journal| author=Lee ES, Lee JM| title=Imaging diagnosis of pancreatic cancer: a state-of-the-art review. | journal=World J Gastroenterol | year= 2014 | volume= 20 | issue= 24 | pages= 7864-77 | pmid=24976723 | doi=10.3748/wjg.v20.i24.7864 | pmc=4069314 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24976723 }} </ref> | |||
CT | *[[Computed tomography|MDCT]] is used as the primary [[imaging]] modality, and is used in conjunction with [[Positron emission tomography|PET]]/[[Computed tomography|CT]]. [[Computed tomography|MDCT]] helps in local and distant disease assessment in a single scan. <ref name="pmid18025509">{{cite journal| author=Brennan DD, Zamboni GA, Raptopoulos VD, Kruskal JB| title=Comprehensive preoperative assessment of pancreatic adenocarcinoma with 64-section volumetric CT. | journal=Radiographics | year= 2007 | volume= 27 | issue= 6 | pages= 1653-66 | pmid=18025509 | doi=10.1148/rg.276075034 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18025509 }} </ref> | ||
*[[Computed tomography|MDCT]] is useful in the evaluation of [[vascular]] involvement, which helps in predicting the [[tumor]] resectability.<ref name="pmid24976723">{{cite journal| author=Lee ES, Lee JM| title=Imaging diagnosis of pancreatic cancer: a state-of-the-art review. | journal=World J Gastroenterol | year= 2014 | volume= 20 | issue= 24 | pages= 7864-77 | pmid=24976723 | doi=10.3748/wjg.v20.i24.7864 | pmc=4069314 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24976723 }} </ref> <ref name="pmid24976723">{{cite journal| author=Lee ES, Lee JM| title=Imaging diagnosis of pancreatic cancer: a state-of-the-art review. | journal=World J Gastroenterol | year= 2014 | volume= 20 | issue= 24 | pages= 7864-77 | pmid=24976723 | doi=10.3748/wjg.v20.i24.7864 | pmc=4069314 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24976723 }} </ref> | |||
*Findings on [[Computed tomography|CT scan]] that may be suggestive of [[pancreatic cancer]] include: <ref name="pmid19129613">{{cite journal| author=Horwhat JD, Gerke H, Acosta RD, Pavey DA, Jowell PS| title=Focal or diffuse "fullness" of the pancreas on CT. Usually benign, but EUS plus/minus FNA is warranted to identify malignancy. | journal=JOP | year= 2009 | volume= 10 | issue= 1 | pages= 37-42 | pmid=19129613 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19129613 }} </ref> <ref name="pmid2827228">{{cite journal| author=Freeny PC, Marks WM, Ryan JA, Traverso LW| title=Pancreatic ductal adenocarcinoma: diagnosis and staging with dynamic CT. | journal=Radiology | year= 1988 | volume= 166 | issue= 1 Pt 1 | pages= 125-33 | pmid=2827228 | doi=10.1148/radiology.166.1.2827228 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2827228 }} </ref><ref name="pmid6867347">{{cite journal| author=Karasawa E, Goldberg HI, Moss AA, Federle MP, London SS| title=CT pancreatogram in carcinoma of the pancreas and chronic pancreatitis. | journal=Radiology | year= 1983 | volume= 148 | issue= 2 | pages= 489-93 | pmid=6867347 | doi=10.1148/radiology.148.2.6867347 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6867347 }} </ref><ref name="pmid9124153">{{cite journal| author=Raptopoulos V, Steer ML, Sheiman RG, Vrachliotis TG, Gougoutas CA, Movson JS| title=The use of helical CT and CT angiography to predict vascular involvement from pancreatic cancer: correlation with findings at surgery. | journal=AJR Am J Roentgenol | year= 1997 | volume= 168 | issue= 4 | pages= 971-7 | pmid=9124153 | doi=10.2214/ajr.168.4.9124153 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9124153 }} </ref><ref name="pmid22699206">{{cite journal| author=Asagi A, Ohta K, Nasu J, Tanada M, Nadano S, Nishimura R et al.| title=Utility of contrast-enhanced FDG-PET/CT in the clinical management of pancreatic cancer: impact on diagnosis, staging, evaluation of treatment response, and detection of recurrence. | journal=Pancreas | year= 2013 | volume= 42 | issue= 1 | pages= 11-9 | pmid=22699206 | doi=10.1097/MPA.0b013e3182550d77 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22699206 }} </ref> | |||
**[[Morphology|Morphological]] changes of the [[gland]] | |||
**Destruction of the peripancreatic fat and loss of the sharp margins with surrounding structures | |||
**Involvement of the regional [[Lymph node|lymph nodes]] and adjacent [[Circulatory system|vasculature]] | |||
**[[Pancreatic duct|Pancreatic ductal]] [[Dilation|dilatation]] | |||
**[[Pancreas|Pancreatic]] atrophy | |||
**[[Obstruction]] of the [[Common bile duct|common bile duct (CBD)]] | |||
[ | [[Image:CT_Pancreatic_cancer.png|thumb|350px|center|By Hellerhoff (Own work) [CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons]] | ||
Image: | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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{{WikiDoc Sources}} | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Mature chapter]] | [[Category:Mature chapter]] | ||
[[Category:Needs overview]] | [[Category:Needs overview]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Surgery]] | |||
[[Category:Gastroenterology]] | |||
Latest revision as of 23:32, 29 July 2020
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American Roentgen Ray Society Images of Pancreatic cancer CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]
Overview
Findings on CT scan that may be suggestive of pancreatic cancer include morphological changes of the gland, destruction of the peripancreatic fat and loss of the sharp margins with surrounding structures, involvement of the regional lymph nodes and adjacent vasculature, pancreatic ductal dilatation, pancreatic atrophy and obstruction of the common bile duct . MDCT (Multi-detector row computed tomography) the imaging modality widely used in suspected pancreatic cancer patients as the pre-operative examination. MDCT is used as the primary imaging modality, and is used in conjunction with PET/CT. MDCT helps in local and distant disease assessment in a single scan. MDCT is useful in the evaluation of vascular involvement, which helps in predicting the tumor resectability.
CT
Pancreatic Adenocarcinoma
- MDCT (Multi-detector row computed tomography) the imaging modality widely used in suspected pancreatic cancer patients as the pre-operative examination. [1]
- MDCT is used as the primary imaging modality, and is used in conjunction with PET/CT. MDCT helps in local and distant disease assessment in a single scan. [2]
- MDCT is useful in the evaluation of vascular involvement, which helps in predicting the tumor resectability.[1] [1]
- Findings on CT scan that may be suggestive of pancreatic cancer include: [3] [4][5][6][7]
- Morphological changes of the gland
- Destruction of the peripancreatic fat and loss of the sharp margins with surrounding structures
- Involvement of the regional lymph nodes and adjacent vasculature
- Pancreatic ductal dilatation
- Pancreatic atrophy
- Obstruction of the common bile duct (CBD)
References
- ↑ 1.0 1.1 1.2 Lee ES, Lee JM (2014). "Imaging diagnosis of pancreatic cancer: a state-of-the-art review". World J Gastroenterol. 20 (24): 7864–77. doi:10.3748/wjg.v20.i24.7864. PMC 4069314. PMID 24976723.
- ↑ Brennan DD, Zamboni GA, Raptopoulos VD, Kruskal JB (2007). "Comprehensive preoperative assessment of pancreatic adenocarcinoma with 64-section volumetric CT". Radiographics. 27 (6): 1653–66. doi:10.1148/rg.276075034. PMID 18025509.
- ↑ Horwhat JD, Gerke H, Acosta RD, Pavey DA, Jowell PS (2009). "Focal or diffuse "fullness" of the pancreas on CT. Usually benign, but EUS plus/minus FNA is warranted to identify malignancy". JOP. 10 (1): 37–42. PMID 19129613.
- ↑ Freeny PC, Marks WM, Ryan JA, Traverso LW (1988). "Pancreatic ductal adenocarcinoma: diagnosis and staging with dynamic CT". Radiology. 166 (1 Pt 1): 125–33. doi:10.1148/radiology.166.1.2827228. PMID 2827228.
- ↑ Karasawa E, Goldberg HI, Moss AA, Federle MP, London SS (1983). "CT pancreatogram in carcinoma of the pancreas and chronic pancreatitis". Radiology. 148 (2): 489–93. doi:10.1148/radiology.148.2.6867347. PMID 6867347.
- ↑ Raptopoulos V, Steer ML, Sheiman RG, Vrachliotis TG, Gougoutas CA, Movson JS (1997). "The use of helical CT and CT angiography to predict vascular involvement from pancreatic cancer: correlation with findings at surgery". AJR Am J Roentgenol. 168 (4): 971–7. doi:10.2214/ajr.168.4.9124153. PMID 9124153.
- ↑ Asagi A, Ohta K, Nasu J, Tanada M, Nadano S, Nishimura R; et al. (2013). "Utility of contrast-enhanced FDG-PET/CT in the clinical management of pancreatic cancer: impact on diagnosis, staging, evaluation of treatment response, and detection of recurrence". Pancreas. 42 (1): 11–9. doi:10.1097/MPA.0b013e3182550d77. PMID 22699206.