PLA2G4C

Phospholipase A2, group IVC (cytosolic, calcium-independent)
Identifiers
Symbols	PLA2G4C ; CPLA2-gamma; DKFZp586C0423
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2748
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE PLA2G4C 209785 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Phospholipase A2, group IVC (cytosolic, calcium-independent), also known as PLA2G4C, is a human gene.

Further reading

• Schröder HC, Perovic S, Kavsan V; et al. (1998). "Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death". Neurotoxicology. 19 (4–5): 683–8. PMID 9745929.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wu T, Angus CW, Yao XL; et al. (1997). "P11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2". J. Biol. Chem. 272 (27): 17145–53. PMID 9202034.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mavoungou E, Georges-Courbot MC, Poaty-Mavoungou V; et al. (1997). "HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes". J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 16 (1): 1–9. PMID 9377118.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Underwood KW, Song C, Kriz RW; et al. (1998). "A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2". J. Biol. Chem. 273 (34): 21926–32. PMID 9705332.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pickard RT, Strifler BA, Kramer RM, Sharp JD (1999). "Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2". J. Biol. Chem. 274 (13): 8823–31. PMID 10085124.CS1 maint: Multiple names: authors list (link)
• Smith JS, Tachibana I, Pohl U; et al. (2000). "A transcript map of the chromosome 19q-arm glioma tumor suppressor region". Genomics. 64 (1): 44–50. doi:10.1006/geno.1999.6101. PMID 10708517.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hartmann C, Johnk L, Sasaki H; et al. (2002). "Novel PLA2G4C polymorphism as a molecular diagnostic assay for 19q loss in human gliomas". Brain Pathol. 12 (2): 178–82. PMID 11958371.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Stewart A, Ghosh M, Spencer DM, Leslie CC (2002). "Enzymatic properties of human cytosolic phospholipase A(2)gamma". J. Biol. Chem. 277 (33): 29526–36. doi:10.1074/jbc.M204856200. PMID 12039969.CS1 maint: Multiple names: authors list (link)
• Lindbom J, Ljungman AG, Lindahl M, Tagesson C (2003). "Increased gene expression of novel cytosolic and secretory phospholipase A(2) types in human airway epithelial cells induced by tumor necrosis factor-alpha and IFN-gamma". J. Interferon Cytokine Res. 22 (9): 947–55. doi:10.1089/10799900260286650. PMID 12396716.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Asai K, Hirabayashi T, Houjou T; et al. (2003). "Human group IVC phospholipase A2 (cPLA2gamma). Roles in the membrane remodeling and activation induced by oxidative stress". J. Biol. Chem. 278 (10): 8809–14. doi:10.1074/jbc.M212117200. PMID 12502717.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jenkins CM, Han X, Yang J; et al. (2004). "Purification of recombinant human cPLA2 gamma and identification of C-terminal farnesylation, proteolytic processing, and carboxymethylation by MALDI-TOF-TOF analysis". Biochemistry. 42 (40): 11798–807. doi:10.1021/bi034611q. PMID 14529291.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dong M, Johnson M, Rezaie A; et al. (2005). "Cytoplasmic phospholipase A2 levels correlate with apoptosis in human colon tumorigenesis". Clin. Cancer Res. 11 (6): 2265–71. doi:10.1158/1078-0432.CCR-04-1079. PMID 15788676.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yan W, Jenkins CM, Han X; et al. (2005). "The highly selective production of 2-arachidonoyl lysophosphatidylcholine catalyzed by purified calcium-independent phospholipase A2gamma: identification of a novel enzymatic mediator for the generation of a key branch point intermediate in eicosanoid signaling". J. Biol. Chem. 280 (29): 26669–79. doi:10.1074/jbc.M502358200. PMID 15908428.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yamashita A, Kamata R, Kawagishi N; et al. (2005). "Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma)". J. Biochem. 137 (5): 557–67. doi:10.1093/jb/mvi067. PMID 15944408.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhao X, Wang D, Zhao Z; et al. (2006). "Caspase-3-dependent activation of calcium-independent phospholipase A2 enhances cell migration in non-apoptotic ovarian cancer cells". J. Biol. Chem. 281 (39): 29357–68. doi:10.1074/jbc.M513105200. PMID 16882668.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mancuso DJ, Han X, Jenkins CM; et al. (2007). "Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma". J. Biol. Chem. 282 (12): 9216–27. doi:10.1074/jbc.M607307200. PMID 17213206.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)