Olanzapine (oral)

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Synonyms / Brand Names: Zyprexa, Zydis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Dosing and Administration

Olanzapine should be administered on a once-a-day schedule without regard to meals, generally beginning with 5 to 10 mg initially, with a target dose of 10 mg/day within several days. Further dosage adjustments, if indicated, should generally occur at intervals of not less than 1 week, since steady state for olanzapine would not be achieved for approximately 1 week in the typical patient. When dosage adjustments are necessary, dose increments/decrements of 5 mg QD are recommended.

For information on dosing for Schizophrenia, Mania, or dosing in Special Populations please refer to Instructions for Administration



FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.

Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.

Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.

Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information

Trial Resources
Ongoing Trials, Trial Results

Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.

Media Resources
Slides, Video, Images, MP3, Podcasts, etc.

Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.

International Resources
en Español






FDA Package Insert Resources

Indications

Contraindications

Side Effects

Drug Interactions

Precautions

Overdose

Instructions for Administration

How Supplied

Pharmacokinetics and Molecular Data

FDA label

FDA on Olanzapine (oral)

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Publication Resources

Most Recent Articles on Olanzapine (oral)

Review Articles on Olanzapine (oral)

Articles on Olanzapine (oral) in N Eng J Med, Lancet, BMJ

WikiDoc State of the Art Review

Textbook Information on Olanzapine (oral)

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Trial Resources

Ongoing Trials with Olanzapine (oral) at Clinical Trials.gov

Trial Results with Olanzapine (oral)

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Guidelines & Evidence Based Medicine Resources

US National Guidelines Clearinghouse on Olanzapine (oral)

Cochrane Collaboration on Olanzapine (oral)

Cost Effectiveness of Olanzapine (oral)

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Media Resources

Powerpoint Slides on Olanzapine (oral)

Images of Olanzapine (oral)

Podcasts & MP3s on Olanzapine (oral)

Videos on Olanzapine (oral)

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Patient Resources

Patient Information from National Library of Medicine

Patient Resources on Olanzapine (oral)

Discussion Groups on Olanzapine (oral)

Patient Handouts on Olanzapine (oral)

Blogs on Olanzapine (oral)

Olanzapine (oral) in the News

Olanzapine (oral) in the Marketplace

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International Resources

Olanzapine (oral) en Español

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Adapted from the FDA Package Insert.