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{{Myelodysplastic syndrome}}
{{Myelodysplastic syndrome}}
{{CMG}}
{{CMG}}; {{AE}} {{NM}}, {{ADS}}
 
==Overview==
==Overview==
Other diagnostic studies for myelodysplastic syndrome include [[bone marrow biopsy]].
==Other Diagnostic Studies==
==Other Diagnostic Studies==
===Bone marrow biopsy===
===Bone Marrow Biopsy===
[[Bone marrow examination]] by an experienced [[hematopathologist]].  This is required to establish the diagnosis, since all hematopathologists recognize a dysplastic marrow as the key feature of myelodysplasia.
*On bone marrow biopsy, findings of myelodysplastic syndrome include:<ref name="TricotWolf-Peeters1984">{{cite journal|last1=Tricot|first1=G.|last2=Wolf-Peeters|first2=C. De|last3=Hendrickx|first3=B.|last4=Verwilghen|first4=R. L.|title=Bone marrow histology in myelodysplastic syndromes.|journal=British Journal of Haematology|volume=57|issue=3|year=1984|pages=423–430|issn=0007-1048|doi=10.1111/j.1365-2141.1984.tb02916.x}}</ref>
 
**[[Erythropoiesis|Abnormal erythropoiesis]]
===Cytogenetics===
**Abnormal myelopoiesis
[[Cytogenetics]] or chromosomal studies. This is ideally performed on the bone marrow aspirate. These require a fresh specimen, since live cells are induced to enter [[metaphase]] to enhance [[chromosomal]] staining.
 
===Flow cytometry===
[[Flow cytometry]] is helpful to establish the presence of any [[lymphoproliferative]] disorder in the [[marrow]]
 
==References==
==References==
{{reflist|2}}
{{reflist|1}}


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Latest revision as of 19:51, 17 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2], Amandeep Singh M.D.[3]

Overview

Other diagnostic studies for myelodysplastic syndrome include bone marrow biopsy.

Other Diagnostic Studies

Bone Marrow Biopsy

References

  1. Tricot, G.; Wolf-Peeters, C. De; Hendrickx, B.; Verwilghen, R. L. (1984). "Bone marrow histology in myelodysplastic syndromes". British Journal of Haematology. 57 (3): 423–430. doi:10.1111/j.1365-2141.1984.tb02916.x. ISSN 0007-1048.


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