Multiple endocrine neoplasia type 2 differential diagnosis: Difference between revisions
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Medullary thyroid carcinoma]] | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Medullary thyroid carcinoma]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" |Medullary thyroid cancer (MTC) is a form of thyroid carcinoma which originates from the parafollicular cells (C cells), which produce the hormone calcitonin. | ||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[C-cell hyperplasia]] | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[C-cell hyperplasia]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" |It is a genetic condition that causes proliferation of C cells of parathyroid gland. | ||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Pheochromocytoma]] | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Pheochromocytoma]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | A neuroendocrine tumor of the medulla of the adrenal glands (originating in the chromaffin cells), or extra-adrenal chromaffin tissue that failed to involute after birth | ||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[VHL (von Hippel Lindau) syndrome]] | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[VHL (von Hippel Lindau) syndrome]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" |An [[autosomal dominant]] genetic disorder causing abnormal growth of [[blood vessel]]s in different parts of the [[body]]. | | style="padding: 5px 5px; background: #F5F5F5;" |An [[autosomal dominant]] genetic disorder causing abnormal growth of [[blood vessel]]s in different parts of the [[body]]. | ||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Hereditary paraganglioma-pheochromocytoma syndrome]] | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Hereditary paraganglioma-pheochromocytoma syndrome]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" |A genetic disorder causing abnormal growth of ganglions along with tumor of the medulla of adrenal gland. | ||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Polycythemia and paraganglioma/pheochromocytoma]] | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Polycythemia and paraganglioma/pheochromocytoma]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" |A genetic disorder causing abnormal growth of [[ganglion]]s and RBC cells. | ||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Neurofibromatosis type 1]] | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Neurofibromatosis type 1]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" |Neurofibromatosis type I is a tumor disorder that is caused by the mutation of a gene on chromosome 17 that is responsible for control of cell division causing tumors along the nervous system. Common symptoms of neurofibromatosis type I include scoliosis (curvature of the spine), learning disabilities, vision disorders, and epilepsy. | ||
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Multiple endocrine neoplasia type 1 (MEN 1)]] | | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Multiple endocrine neoplasia type 1 (MEN 1)]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" |An [[autosomal dominant]] genetic disorder causing | | style="padding: 5px 5px; background: #F5F5F5;" |An [[autosomal dominant]] genetic disorder causing tumors of parathyroid, pancreas and pituitary gland. | ||
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Revision as of 15:48, 22 September 2015
Multiple endocrine neoplasia type 2 Microchapters |
Differentiating Multiple endocrine neoplasia type 2 from other Diseases |
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Diagnosis |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Differential Diagnosis
Multiple endocrine neoplasia type 2 must be differentiated from following hereditary diseases.
Disease | Definition |
---|---|
Medullary thyroid carcinoma | Medullary thyroid cancer (MTC) is a form of thyroid carcinoma which originates from the parafollicular cells (C cells), which produce the hormone calcitonin. |
C-cell hyperplasia | It is a genetic condition that causes proliferation of C cells of parathyroid gland. |
Pheochromocytoma | A neuroendocrine tumor of the medulla of the adrenal glands (originating in the chromaffin cells), or extra-adrenal chromaffin tissue that failed to involute after birth |
VHL (von Hippel Lindau) syndrome | An autosomal dominant genetic disorder causing abnormal growth of blood vessels in different parts of the body. |
Hereditary paraganglioma-pheochromocytoma syndrome | A genetic disorder causing abnormal growth of ganglions along with tumor of the medulla of adrenal gland. |
Polycythemia and paraganglioma/pheochromocytoma | A genetic disorder causing abnormal growth of ganglions and RBC cells. |
Neurofibromatosis type 1 | Neurofibromatosis type I is a tumor disorder that is caused by the mutation of a gene on chromosome 17 that is responsible for control of cell division causing tumors along the nervous system. Common symptoms of neurofibromatosis type I include scoliosis (curvature of the spine), learning disabilities, vision disorders, and epilepsy. |
Multiple endocrine neoplasia type 1 (MEN 1) | An autosomal dominant genetic disorder causing tumors of parathyroid, pancreas and pituitary gland. |