Multiple endocrine neoplasia type 1 MRI: Difference between revisions

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==MRI==
==MRI==
===Gastrointestinal Neuroendocrine Tumors===
===Gastrointestinal Neuroendocrine Tumors===
* [[MRI]] is used for suspected hepatic, pancreatic or retroperitoneal [[neuroendocrine tumor]]s, often with [[gadolinium]] contrast.<ref name=Radiopaedia012015>{{cite web | title = Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]| url = http://radiopaedia.org/articles/gastrointestinal-neuroendocrine-tumours-3 }}</ref>
* [[MRI]] is used for suspected hepatic, pancreatic or retroperitoneal [[neuroendocrine tumor]]s, often with [[gadolinium]] contrast.<ref name=Radiopaedia012015>{{cite web | title = Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]| url = http://radiopaedia.org/articles/gastrointestinal-neuroendocrine-tumours-3 }}</ref> <ref name="pmid24213321">{{cite journal| author=Tonelli F, Giudici F, Giusti F, Brandi ML| title=Gastroenteropancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1. | journal=Cancers (Basel) | year= 2012 | volume= 4 | issue= 2 | pages= 504-22 | pmid=24213321 | doi=10.3390/cancers4020504 | pmc=3712700 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24213321  }} </ref>
* [[MRI]] enterography is also possible
* [[MRI]] enterography is also possible



Revision as of 18:57, 6 October 2017

Multiple endocrine neoplasia type 1 Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

MRI may be helpful in the diagnosis of multiple endocrine neoplasia type 1. Findings on MRI suggestive of multiple endocrine neoplasia type 1 include diffuse heterogenous enhancement of T1 C+ (Gd), low T1 signal and high T2 signal.

MRI

Gastrointestinal Neuroendocrine Tumors

Insulinoma

  • T1 C+ (Gd): typically shows enhancement, although contrast enhancement may not improve tumor visualisation compared with non-contrast images

Somatostatinoma

  • Smaller lesions may be difficult to diagnose.
  • Signal characteristics of larger lesion include:[5]
  • T1: low signal
  • T2: high signal
  • T1 (C+) Gd: most show early diffuse heterogenous enhancement

References

  1. "Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]".
  2. Tonelli F, Giudici F, Giusti F, Brandi ML (2012). "Gastroenteropancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1". Cancers (Basel). 4 (2): 504–22. doi:10.3390/cancers4020504. PMC 3712700. PMID 24213321.
  3. Owen NJ, Sohaib SA, Peppercorn PD, Monson JP, Grossman AB, Besser GM; et al. (2001). "MRI of pancreatic neuroendocrine tumours". Br J Radiol. 74 (886): 968–73. doi:10.1259/bjr.74.886.740968. PMID 11675319.
  4. "Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]".
  5. "Radiopedia2015 Somatostatinoma [Dr Yuranga Weerakkody]".

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