Multiple endocrine neoplasia type 1 CT: Difference between revisions
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==CT== | ==CT== | ||
* [[CT]] is used for suspected gastric, enteric and pancreatic [[neuroendocrine tumor]]s with pre and post IV iodinated contrast.<ref name=Radiopaedia012015>{{cite web | title = Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]| url = http://radiopaedia.org/articles/gastrointestinal-neuroendocrine-tumours-3 }}</ref> | * [[CT]] is used for suspected gastric, enteric and pancreatic [[neuroendocrine tumor]]s with pre and post IV iodinated contrast.<ref name=Radiopaedia012015>{{cite web | title = Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]| url = http://radiopaedia.org/articles/gastrointestinal-neuroendocrine-tumours-3 }}</ref> | ||
* [[Bowel]] distension with [[fluid]], either by [[oral]] intake (CT enterography) or via an nasojejunal tube (CT [[enteroclysis]]), improves detection of primary gastrointestinal [[neuroendocrine tumor]]s. | * [[Bowel]] distension with [[fluid]], either by [[oral]] intake (CT enterography) or via an nasojejunal tube (CT [[enteroclysis]]), improves detection of primary gastrointestinal [[neuroendocrine tumor]]s. |
Revision as of 19:55, 17 October 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Abdominal CT scan may be helpful in the diagnosing pancreatic involvement of multiple endocrine neoplasia type 1. Findings on CT scan suggestive of pancreatic involvement of multiple endocrine neoplasia type 1 include thickened stomach rugal folds, multiple gastric nodules and calcified or cystic pancreatic tumors.
CT
- CT is used for suspected gastric, enteric and pancreatic neuroendocrine tumors with pre and post IV iodinated contrast.[1]
- Bowel distension with fluid, either by oral intake (CT enterography) or via an nasojejunal tube (CT enteroclysis), improves detection of primary gastrointestinal neuroendocrine tumors.
Zollinger-Ellison Syndrome
- Common CT findings of Zollinger-Ellison syndrome include the following:[2]
Insulinoma
- They tend to be hyper-attenuating on arterial phase so arterial or pancreatic phased imaging may aid in better detection. Some may show calcification.[5]
Pancreatic Islet Cell Tumors
- Multiphase contrast enhanced thin slice cross-sectional imaging is ideal.
- Tumors tend to be smaller, hypervascular and may be calcified or cystic.[6]
Gastrinoma
- Gastinomas are usually malignant and as they are frequently multiple and often extrapancreatic (90% located in the gastrinoma triangle) they can be difficult to locate. As such multiphase contrast enhanced thin slice cross-sectional imaging is ideal.[7]
- Tumor size is variable, but the size of pancreatic lesions varies from 3-4 cm.
- The lesions are often hypervascular, so they may be visible on arterial phase CT and angiography.
Glucagonoma
- Common CT findings of glucagonoma include the following:[8]
References
- ↑ "Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]".
- ↑ "Radiopedia2015 Zollinger-Ellison syndrome [Dr Henry Knipe]".
- ↑ King AD, Ko GT, Yeung VT, Chow CC, Griffith J, Cockram CS (1998). "Dual phase spiral CT in the detection of small insulinomas of the pancreas". Br J Radiol. 71 (841): 20–3. doi:10.1259/bjr.71.841.9534694. PMID 9534694.
- ↑ Fidler JL, Fletcher JG, Reading CC, Andrews JC, Thompson GB, Grant CS; et al. (2003). "Preoperative detection of pancreatic insulinomas on multiphasic helical CT". AJR Am J Roentgenol. 181 (3): 775–80. doi:10.2214/ajr.181.3.1810775. PMID 12933480.
- ↑ "Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]".
- ↑ "Radiopedia2015 Endocrine tumours of the pancreas [Dr Yuranga Weerakkody and Radswiki]".
- ↑ "Radiopedia2015 Gastrinoma [Dr Frank Gaillard]".
- ↑ "Radiopedia2015 Glucagonoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]".