Multiple endocrine neoplasia type 1 CT: Difference between revisions
Irfan Dotani (talk | contribs) No edit summary |
|||
Line 2: | Line 2: | ||
{{Multiple endocrine neoplasia type 1}} | {{Multiple endocrine neoplasia type 1}} | ||
{{CMG}}; {{AE}} {{Ammu}} | {{CMG}}; {{AE}} {{Ammu}} | ||
==Overview== | ==Overview== | ||
Abdominal [[CT]] scan may be helpful in the [[diagnosis]] of multiple endocrine neoplasia type 1. Findings on [[CT]] scan suggestive of multiple endocrine neoplasia type 1 include thickened [[stomach]] rugal folds, multiple gastric [[nodule]]s and calcified or cystic [[pancreatic tumor]]s. | Abdominal [[CT]] scan may be helpful in the [[diagnosis]] of multiple endocrine neoplasia type 1. Findings on [[CT]] scan suggestive of multiple endocrine neoplasia type 1 include thickened [[stomach]] rugal folds, multiple gastric [[nodule]]s and calcified or cystic [[pancreatic tumor]]s. | ||
Line 15: | Line 16: | ||
:* Thickened rugal folds | :* Thickened rugal folds | ||
:* Multiple gastric nodules/masses<ref name="pmid9534694">{{cite journal| author=King AD, Ko GT, Yeung VT, Chow CC, Griffith J, Cockram CS| title=Dual phase spiral CT in the detection of small insulinomas of the pancreas. | journal=Br J Radiol | year= 1998 | volume= 71 | issue= 841 | pages= 20-3 | pmid=9534694 | doi=10.1259/bjr.71.841.9534694 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9534694 }} </ref><ref name="pmid12933480">{{cite journal| author=Fidler JL, Fletcher JG, Reading CC, Andrews JC, Thompson GB, Grant CS et al.| title=Preoperative detection of pancreatic insulinomas on multiphasic helical CT. | journal=AJR Am J Roentgenol | year= 2003 | volume= 181 | issue= 3 | pages= 775-80 | pmid=12933480 | doi=10.2214/ajr.181.3.1810775 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12933480 }} </ref> | :* Multiple gastric nodules/masses<ref name="pmid9534694">{{cite journal| author=King AD, Ko GT, Yeung VT, Chow CC, Griffith J, Cockram CS| title=Dual phase spiral CT in the detection of small insulinomas of the pancreas. | journal=Br J Radiol | year= 1998 | volume= 71 | issue= 841 | pages= 20-3 | pmid=9534694 | doi=10.1259/bjr.71.841.9534694 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9534694 }} </ref><ref name="pmid12933480">{{cite journal| author=Fidler JL, Fletcher JG, Reading CC, Andrews JC, Thompson GB, Grant CS et al.| title=Preoperative detection of pancreatic insulinomas on multiphasic helical CT. | journal=AJR Am J Roentgenol | year= 2003 | volume= 181 | issue= 3 | pages= 775-80 | pmid=12933480 | doi=10.2214/ajr.181.3.1810775 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12933480 }} </ref> | ||
===Insulinoma=== | ===Insulinoma=== | ||
* They tend to be hyper-attenuating on arterial phase so arterial or pancreatic phased imaging may aid in better detection. Some may show [[calcification]].<ref name=Radiopaedia032015>{{cite web | title = Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/insulinoma }}</ref> | * They tend to be hyper-attenuating on arterial phase so arterial or pancreatic phased imaging may aid in better detection. Some may show [[calcification]].<ref name=Radiopaedia032015>{{cite web | title = Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]| url = http://radiopaedia.org/articles/insulinoma }}</ref> | ||
Line 33: | Line 35: | ||
:* [[Tumor]]s may be solid or contain central low-attenuation areas on [[CT]]. | :* [[Tumor]]s may be solid or contain central low-attenuation areas on [[CT]]. | ||
== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category: | [[Category:Oncology]] | ||
{{WS}} | |||
{{WH}} |
Revision as of 15:41, 21 July 2016
Multiple endocrine neoplasia type 1 Microchapters |
Differentiating Multiple endocrine neoplasia type 1 from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Multiple endocrine neoplasia type 1 CT On the Web |
American Roentgen Ray Society Images of Multiple endocrine neoplasia type 1 CT |
Directions to Hospitals Treating Multiple endocrine neoplasia type 1 |
Risk calculators and risk factors for Multiple endocrine neoplasia type 1 CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Abdominal CT scan may be helpful in the diagnosis of multiple endocrine neoplasia type 1. Findings on CT scan suggestive of multiple endocrine neoplasia type 1 include thickened stomach rugal folds, multiple gastric nodules and calcified or cystic pancreatic tumors.
CT
Gastrointestinal Neuroendocrine Tumors
- CT is used for suspected gastric, enteric and pancreatic neuroendocrine tumors with pre and post IV iodinated contrast.[1]
- Bowel distension with fluid, either by oral intake (CT enterography) or via an nasojejunal tube (CT enteroclysis), improves detection of primary gastrointestinal neuroendocrine tumors.
Zollinger-Ellison Syndrome
- Common CT findings of Zollinger-Ellison syndrome include the following:[2]
Insulinoma
- They tend to be hyper-attenuating on arterial phase so arterial or pancreatic phased imaging may aid in better detection. Some may show calcification.[5]
Pancreatic Islet Cell Tumors
- Multiphase contrast enhanced thin slice cross-sectional imaging is ideal.
- Tumors tend to be smaller, hypervascular and may be calcified or cystic.[6]
Gastrinoma
- Gastinomas are usually malignant and as they are frequently multiple and often extrapancreatic (90% located in the gastrinoma triangle) they can be difficult to locate. As such multiphase contrast enhanced thin slice cross-sectional imaging is ideal.[7]
- Tumor size is variable, but the size of pancreatic lesions varies from 3-4 cm.
- The lesions are often hypervascular, so they may be visible on arterial phase CT and angiography.
Glucagonoma
- Common CT findings of glucagonoma include the following:[8]
References
- ↑ "Radiopedia2015 Gastrointestinal neuroendocrine tumours [Dr Dalia Ibrahim and Dr Jan Smith]".
- ↑ "Radiopedia2015 Zollinger-Ellison syndrome [Dr Henry Knipe]".
- ↑ King AD, Ko GT, Yeung VT, Chow CC, Griffith J, Cockram CS (1998). "Dual phase spiral CT in the detection of small insulinomas of the pancreas". Br J Radiol. 71 (841): 20–3. doi:10.1259/bjr.71.841.9534694. PMID 9534694.
- ↑ Fidler JL, Fletcher JG, Reading CC, Andrews JC, Thompson GB, Grant CS; et al. (2003). "Preoperative detection of pancreatic insulinomas on multiphasic helical CT". AJR Am J Roentgenol. 181 (3): 775–80. doi:10.2214/ajr.181.3.1810775. PMID 12933480.
- ↑ "Radiopedia2015 Insulinoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]".
- ↑ "Radiopedia2015 Endocrine tumours of the pancreas [Dr Yuranga Weerakkody and Radswiki]".
- ↑ "Radiopedia2015 Gastrinoma [Dr Frank Gaillard]".
- ↑ "Radiopedia2015 Glucagonoma [Dr Yuranga Weerakkody and Dr Frank Gaillard]".