Mixed connective tissue disease natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
==Natural History, Complications, and Prognosis== | ==Natural History, Complications, and Prognosis== | ||
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===Prognosis=== | ===Prognosis=== | ||
*In MCTD, the worst prognosis and high mortality rate are associated with the presence of pulmonary involvement.<ref name="pmid22424193">{{cite journal |vauthors=Ortega-Hernandez OD, Shoenfeld Y |title=Mixed connective tissue disease: an overview of clinical manifestations, diagnosis and treatment |journal=Best Pract Res Clin Rheumatol |volume=26 |issue=1 |pages=61–72 |date=February 2012 |pmid=22424193 |doi=10.1016/j.berh.2012.01.009 |url=}}</ref> | *In MCTD, the worst prognosis and high mortality rate are associated with the presence of pulmonary involvement.<ref name="pmid22424193">{{cite journal |vauthors=Ortega-Hernandez OD, Shoenfeld Y |title=Mixed connective tissue disease: an overview of clinical manifestations, diagnosis and treatment |journal=Best Pract Res Clin Rheumatol |volume=26 |issue=1 |pages=61–72 |date=February 2012 |pmid=22424193 |doi=10.1016/j.berh.2012.01.009 |url=}}</ref> | ||
==References== | ==References== |
Revision as of 16:33, 2 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of MCTD include:[1]
- Polyarthritis
- Raynaud's phenomenon
- Puffy fingers
- Interstitial lung disease
- Esophageal dysmotility
- Sclerodactyly
- Polymyositis
Prognosis
- In MCTD, the worst prognosis and high mortality rate are associated with the presence of pulmonary involvement.[2]
References
- ↑ Tani C, Carli L, Vagnani S, Talarico R, Baldini C, Mosca M, Bombardieri S (2014). "The diagnosis and classification of mixed connective tissue disease". J. Autoimmun. 48-49: 46–9. doi:10.1016/j.jaut.2014.01.008. PMID 24461387.
- ↑ Ortega-Hernandez OD, Shoenfeld Y (February 2012). "Mixed connective tissue disease: an overview of clinical manifestations, diagnosis and treatment". Best Pract Res Clin Rheumatol. 26 (1): 61–72. doi:10.1016/j.berh.2012.01.009. PMID 22424193.