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{{Melanoma}}


==Overview==
==Overview==
There are no [[Medical laboratory|laboratory]] findings associated with the [[diagnosis]] of melanoma. [[Serum]] [[lactate dehydrogenase|lactate dehydrogenase (LDH)]] may be elevated among [[Patient|patients]] with [[metastasis]].
==Laboratory Findings==
*There are no [[Medical laboratory|laboratory]] findings associated with the [[diagnosis]] of melanoma. Measurement of [[serum]] [[Lactate dehydrogenase|LDH]] may be considered for follow-up among [[Patient|patients]] who have been [[Diagnosis|diagnosed]] with [[Cancer staging|stage]] IB-IV melanoma.<ref name="pmid23584343">{{cite journal| author=Coit DG, Andtbacka R, Anker CJ, Bichakjian CK, Carson WE, Daud A et al.| title=Melanoma, version 2.2013: featured updates to the NCCN guidelines. | journal=J Natl Compr Canc Netw | year= 2013 | volume= 11 | issue= 4 | pages= 395-407 | pmid=23584343 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23584343  }} </ref>
===Lactate Dehydrogenase (LDH)===
*Once [[Metastasis|metastatic]] melanoma is [[Diagnosis|diagnosed]], serum [[lactate dehydrogenase|lactate dehydrogenase (LDH)]] may be helpful for follow-up.<ref name="pmid23584343">{{cite journal| author=Coit DG, Andtbacka R, Anker CJ, Bichakjian CK, Carson WE, Daud A et al.| title=Melanoma, version 2.2013: featured updates to the NCCN guidelines. | journal=J Natl Compr Canc Netw | year= 2013 | volume= 11 | issue= 4 | pages= 395-407 | pmid=23584343 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23584343  }} </ref>
*For [[Patient|patients]] with [[Cancer staging|stage]] IB-IV melanoma, measurement of [[serum]] [[Lactate dehydrogenase|LDH]] may be considered every 6-12 months.<ref name="pmid23584343">{{cite journal| author=Coit DG, Andtbacka R, Anker CJ, Bichakjian CK, Carson WE, Daud A et al.| title=Melanoma, version 2.2013: featured updates to the NCCN guidelines. | journal=J Natl Compr Canc Netw | year= 2013 | volume= 11 | issue= 4 | pages= 395-407 | pmid=23584343 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23584343  }} </ref>


==LDH==
[[Lactate dehydrogenase]] (LDH) tests are often used to screen for [[metastasis|metastases]], although many patients with metastases (even end-stage) have a normal LDH; extraordinarily high LDH often indicates metastatic spread of the disease to the liver.  It is common for patients diagnosed with melanoma to have chest X-rays and an LDH test, and in some cases [[computed tomography|CT]], [[MRI]], [[Positron emission tomography|PET]] and/or PET/CT scans.  Although controversial, sentinel [[lymph node]] biopsies and examination of the lymph nodes are also performed in patients to assess spread to the lymph nodes.
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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Latest revision as of 20:38, 3 January 2019


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Serge Korjian M.D.

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Overview

There are no laboratory findings associated with the diagnosis of melanoma. Serum lactate dehydrogenase (LDH) may be elevated among patients with metastasis.

Laboratory Findings

Lactate Dehydrogenase (LDH)

References

  1. 1.0 1.1 1.2 Coit DG, Andtbacka R, Anker CJ, Bichakjian CK, Carson WE, Daud A; et al. (2013). "Melanoma, version 2.2013: featured updates to the NCCN guidelines". J Natl Compr Canc Netw. 11 (4): 395–407. PMID 23584343.