Marburg hemorrhagic fever natural history, complications and prognosis: Difference between revisions
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Case fatality rates in Marburg hemorrhagic fever outbreaks have ranged from 23% to 90%. | Case fatality rates in Marburg hemorrhagic fever outbreaks have ranged from 23% to 90%. | ||
==Natural History== | ==Natural History== | ||
* | *Humans and nonhuman primates are susceptible to [[Filoviridae|filovirus infection]] and are considered to be end hosts. | ||
*Surveys to identify animal reservoirs and arthropod vectors have been aggressively undertaken in endemic areas, particularly after most large filovirus outbreaks. | *Surveys to identify animal reservoirs and arthropod vectors have been aggressively undertaken in endemic areas, particularly after most large filovirus outbreaks. | ||
*If left untreated symptoms of marburg hemorrhagic fever become increasingly severe and can include jaundice, inflammation of the pancreas, severe weight loss, delirium, shock, liver failure, massive | *If left untreated symptoms of marburg hemorrhagic fever become increasingly severe and can include [[jaundice]], inflammation of the pancreas, severe [[weight loss]], [[delirium]], [[shock]], [[Liver failure|liver failure,]] massive [[hemorrhage]], and [[Multiorgan failure|multi-organ dysfunction]]. | ||
*Because many of the signs and symptoms of Marburg hemorrhagic fever are similar to those of other infectious diseases such as malaria or typhoid fever, clinical diagnosis of the disease can be difficult, especially if only a single case is involved. | *Because many of the signs and symptoms of Marburg hemorrhagic fever are similar to those of other infectious diseases such as [[malaria]] or [[typhoid fever]], clinical diagnosis of the disease can be difficult, especially if only a single case is involved. | ||
==Complications== | ==Complications== | ||
Common complications of marburg hemorrhagic fever include: | Common complications of marburg hemorrhagic fever include: | ||
*Orchitis | *[[Epididymoorchitis|Orchitis]] | ||
*Transverse myelitis | *[[Transverse myelitis]] | ||
* | *[[Parotitis]] | ||
*Pancreatic hemorrhage | *Pancreatic hemorrhage | ||
*Chronic hepatitis | *[[Chronic hepatitis]] | ||
==Prognosis== | ==Prognosis== | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] |
Revision as of 17:32, 20 October 2017
Marburg hemorrhagic fever Microchapters |
Differentiating Marburg hemorrhagic fever from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief:
Overview
Case fatality rates in Marburg hemorrhagic fever outbreaks have ranged from 23% to 90%.
Natural History
- Humans and nonhuman primates are susceptible to filovirus infection and are considered to be end hosts.
- Surveys to identify animal reservoirs and arthropod vectors have been aggressively undertaken in endemic areas, particularly after most large filovirus outbreaks.
- If left untreated symptoms of marburg hemorrhagic fever become increasingly severe and can include jaundice, inflammation of the pancreas, severe weight loss, delirium, shock, liver failure, massive hemorrhage, and multi-organ dysfunction.
- Because many of the signs and symptoms of Marburg hemorrhagic fever are similar to those of other infectious diseases such as malaria or typhoid fever, clinical diagnosis of the disease can be difficult, especially if only a single case is involved.
Complications
Common complications of marburg hemorrhagic fever include:
- Orchitis
- Transverse myelitis
- Parotitis
- Pancreatic hemorrhage
- Chronic hepatitis
Prognosis
Case fatality rates in Marburg hemorrhagic fever outbreaks have ranged from 23% to 90%.