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==Overview==
==Overview==
'''Macrocytosis''' is the enlargement of [[red blood cell]]s with near-constant [[haemoglobin]] concentration, and is defined by a [[mean corpuscular volume]] (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories).  
An [[ECG]] may be helpful in the diagnosis of [[megaloblastic anemia]], though the ECG findings are not specific to a diagnosis of megaloblastic anemia. Findings on an ECG suggestive of/diagnostic of [[megaloblastic anemia]] include  [[T wave inversions]], [[ST-segment depression]], [[LVH]].
 
==Electrocardiogram==
 
*An [[ECG]] may be helpful in the diagnosis of [[megaloblastic anemia]]. Findings on an [[ECG]] suggestive of/diagnostic of [[megaloblastic anemia]] include:<ref name="pmid25838876">{{cite journal |vauthors=Shamkani WA, Jafar NS, Narayanan SR, Rajappan AK |title=Acute Myocardial Infarction in a Young Lady due to Vitamin B12 Deficiency Induced Hyperhomocysteinemia |journal=Heart Views |volume=16 |issue=1 |pages=25–9 |date=2015 |pmid=25838876 |pmc=4379639 |doi=10.4103/1995-705X.152998 |url=}}</ref><ref name="pmid24959433">{{cite journal |vauthors=Gv S, Pk S, Herur A, Chinagudi S, Patil SS, Ankad RB, Badami SV |title=Correlation Between Haemoglobin Level and Electrocardiographic (ECG) Findings in Anaemia: A Cross-Sectional Study |journal=J Clin Diagn Res |volume=8 |issue=4 |pages=BC04–6 |date=April 2014 |pmid=24959433 |pmc=4064835 |doi=10.7860/JCDR/2014/8966.4202 |url=}}</ref>
** [[T wave inversions]]
** [[ST segment depression]]
**[[Left ventricular hypertrophy|LVH]]
** Tachycardia (which can be found in a variety of anemia subtypes)
*[[Vitamin B12 Deficiency|Vitamin B12 deficiency]] is associated with [[hyperhomocysteinemia]] and can cause acute [[myocardial infarction]]. Features of [[myocardial infarction]] can appear in [[ECG]].
 
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[es:Anemia megaloblástica]]
 
[[gl:Anemia megaloblástica]]
[[he:אנמיה מגלובלסטית]]
[[it:Anemia megaloblastica]]
[[pl:Niedokrwistość megaloblastyczna]]
[[pt:Anemia megaloblástica]]
[[ru:Пернициозная анемия]]
[[sl:Megaloblastna anemija]]
[[sr:Мегалобластна анемија]]
[[tr:Megaloblastik anemi]]


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Latest revision as of 23:34, 2 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2] Associate Editor(s)-in-Chief: Omer Kamal, M.D.[3] Amandeep Singh M.D.[4]

Overview

An ECG may be helpful in the diagnosis of megaloblastic anemia, though the ECG findings are not specific to a diagnosis of megaloblastic anemia. Findings on an ECG suggestive of/diagnostic of megaloblastic anemia include T wave inversions, ST-segment depression, LVH.

Electrocardiogram

References

  1. Shamkani WA, Jafar NS, Narayanan SR, Rajappan AK (2015). "Acute Myocardial Infarction in a Young Lady due to Vitamin B12 Deficiency Induced Hyperhomocysteinemia". Heart Views. 16 (1): 25–9. doi:10.4103/1995-705X.152998. PMC 4379639. PMID 25838876.
  2. Gv S, Pk S, Herur A, Chinagudi S, Patil SS, Ankad RB, Badami SV (April 2014). "Correlation Between Haemoglobin Level and Electrocardiographic (ECG) Findings in Anaemia: A Cross-Sectional Study". J Clin Diagn Res. 8 (4): BC04–6. doi:10.7860/JCDR/2014/8966.4202. PMC 4064835. PMID 24959433.


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