MFGE8

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Milk fat globule-EGF factor 8 protein
Identifiers
Symbols MFGE8 ; BA46; EDIL1; HsT19888; OAcGD3S
External IDs Template:OMIM5 Template:MGI HomoloGene4334
RNA expression pattern
File:PBB GE MFGE8 210605 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Milk fat globule-EGF factor 8 protein, also known as MFGE8, is a human gene.[1]


References

  1. "Entrez Gene: MFGE8 milk fat globule-EGF factor 8 protein".

Further reading

  • Peterson JA, Scallan CD, Ceriani RL, Hamosh M (2002). "Structural and functional aspects of three major glycoproteins of the human milk fat globule membrane". Adv. Exp. Med. Biol. 501: 179–87. PMID 11787681.
  • Larocca D, Peterson JA, Urrea R; et al. (1991). "A Mr 46,000 human milk fat globule protein that is highly expressed in human breast tumors contains factor VIII-like domains". Cancer Res. 51 (18): 4994–8. PMID 1909932.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
  • Couto JR, Taylor MR, Godwin SG; et al. (1996). "Cloning and sequence analysis of human breast epithelial antigen BA46 reveals an RGD cell adhesion sequence presented on an epidermal growth factor-like domain". DNA Cell Biol. 15 (4): 281–6. PMID 8639264.
  • Collins C, Nehlin JO, Stubbs JD; et al. (1997). "Mapping of a newly discovered human gene homologous to the apoptosis associated-murine mammary protein, MFG-E8, to chromosome 15q25". Genomics. 39 (1): 117–8. doi:10.1006/geno.1996.4425. PMID 9027496.
  • Aoki N, Ishii T, Ohira S; et al. (1997). "Stage specific expression of milk fat globule membrane glycoproteins in mouse mammary gland: comparison of MFG-E8, butyrophilin, and CD36 with a major milk protein, beta-casein". Biochim. Biophys. Acta. 1334 (2–3): 182–90. PMID 9101712.
  • Taylor MR, Couto JR, Scallan CD; et al. (1997). "Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion". DNA Cell Biol. 16 (7): 861–9. PMID 9260929.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
  • Giuffrida MG, Cavaletto M, Giunta C; et al. (1998). "Isolation and characterization of full and truncated forms of human breast carcinoma protein BA46 from human milk fat globule membranes". J. Protein Chem. 17 (2): 143–8. PMID 9535276.
  • Newburg DS, Peterson JA, Ruiz-Palacios GM; et al. (1998). "Role of human-milk lactadherin in protection against symptomatic rotavirus infection". Lancet. 351 (9110): 1160–4. PMID 9643686.
  • Peterson JA, Hamosh M, Scallan CD; et al. (1998). "Milk fat globule glycoproteins in human milk and in gastric aspirates of mother's milk-fed preterm infants". Pediatr. Res. 44 (4): 499–506. PMID 9773837.
  • Häggqvist B, Näslund J, Sletten K; et al. (1999). "Medin: an integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid". Proc. Natl. Acad. Sci. U.S.A. 96 (15): 8669–74. PMID 10411933.
  • Oshima K, Aoki N, Kato T; et al. (2002). "Secretion of a peripheral membrane protein, MFG-E8, as a complex with membrane vesicles". Eur. J. Biochem. 269 (4): 1209–18. PMID 11856354.
  • Hanayama R, Tanaka M, Miwa K; et al. (2002). "Identification of a factor that links apoptotic cells to phagocytes". Nature. 417 (6885): 182–7. doi:10.1038/417182a. PMID 12000961.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Lee SH, Seo GS, Park PH; et al. (2003). "Increased expression of O-acetyl disialoganglioside synthase during rat liver fibrogenesis relates to stellate cell activation". Biochem. Biophys. Res. Commun. 303 (3): 954–61. PMID 12670504.
  • Rehman KS, Yin S, Mayhew BA; et al. (2004). "Human myometrial adaptation to pregnancy: cDNA microarray gene expression profiling of myometrium from non-pregnant and pregnant women". Mol. Hum. Reprod. 9 (11): 681–700. PMID 14561811.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Reches M, Gazit E (2005). "Amyloidogenic hexapeptide fragment of medin: homology to functional islet amyloid polypeptide fragments". Amyloid. 11 (2): 81–9. PMID 15478463.

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