MALT lymphoma staging: Difference between revisions
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{{CMG}}{{AE}}{{SR}}, {{AY}} | |||
{{MALT lymphoma}} | {{MALT lymphoma}} | ||
==Overview== | |||
The staging of MALT lymphoma is based on two staging systems: Ann Arbor staging system and the TNM staging system.<ref name=stagingmaltlymphoma1>Staging MALT lymphoma of the stomach. Canadian Cancer Society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/malt-lymphoma/?region=on. Accessed on January 25, 2016</ref> | |||
==Staging== | |||
The staging of MALT lymphoma is based on two staging systems: Ann Arbor staging system and the TNM staging system.<ref name=stagingmaltlymphoma1>Staging MALT lymphoma of the stomach. Canadian Cancer Society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/malt-lymphoma/?region=on. Accessed on January 25, 2016</ref> | |||
===Ann Arbor Staging System=== | |||
The Ann Arbor staging system has been modified for gastric MALT lymphoma.<ref name=stagingmaltlymphoma1>Staging MALT lymphoma of the stomach. Canadian Cancer Society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/malt-lymphoma/?region=on. Accessed on January 25, 2016</ref> | |||
{| style="border: 0px; font-size: 90%; margin: 3px; width:1000px" | |||
|valign=top| | |||
|+ | |||
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Stage}} | |||
! style="background: #4479BA; width: 800px;" | {{fontcolor|#FFF|Description}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | | |||
Stage I | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
Tumor is confined to the stomach without spread to the lymph nodes | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" align=center | | |||
Stage II | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
Tumor extends into the abdomen and has spread to the lymph nodes | |||
*'''II1''': Cancer has spread to local lymph nodes (such as [[paragastric nodes]]) | |||
*'''II2''': Cancer has spread to distant lymph nodes (such as [[para-aortic]], [[pelvic]], or [[inguinal nodes]]) | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" align=center | | |||
Stage IIE | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
Tumor penetrates the serosa to spread to adjacent organs or tissues | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" align=center| | |||
Stage IV | |||
| style="padding: 5px 5px; background: #F5F5F5;" | | |||
Disseminated spread to extranodal sites or spread to the lymph nodes above the diaphragm (supradiaphragmatic nodal involvement) | |||
|} | |||
===TNM Staging System=== | |||
The TNM staging system for stomach cancer has also been applied to gastric MALT lymphoma. TNM stands for tumor, nodes, and metastasis.<ref name=stagingmaltlymphoma1>Staging MALT lymphoma of the stomach. Canadian Cancer Society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/malt-lymphoma/?region=on. Accessed on January 25, 2016</ref> | |||
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center | |||
|valign=top| | |||
|+ | |||
! style="background: #4479BA; width: 100px;" | {{fontcolor|#FFF|TNM Classification}} | |||
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Definition}} | |||
|- | |||
| style="padding: 0 5px; background: #4479BA" colspan=3 |{{fontcolor|#FFF|Primary Tumor (T)}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |T1 | |||
| style="padding: 5px 5px; background: #F5F5F5;" |The lymphoma is confined to the mucosa or submucosa | |||
*'''T1m''': Lymphoma confined to the mucosa | |||
*'''T1sm''': Lymphoma confined to the submucosa | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |T2 | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Lymphoma invades the muscularis propria | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |T3 | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Lymphoma penetrates the subserosa | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |T4 | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Lymphoma has grown through the serosa or invades organs near the stomach | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |T1a | |||
| style="padding: 5px 5px; background: #F5F5F5;" |[[Tumor]] invades subepithelial [[connective tissue]], but has no lymphovascular invasion | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |T1b | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Tumor invades subepithelial connective tissue and has spread to the [[lymphatic]] channels or [[blood vessels]] | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |T2 | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Tumor invades the [[erectile tissue]] ([[corpus spongiosum]] or cavernosum) | |||
|- | |||
| style="padding: 0 5px; background: #4479BA" colspan=3 |{{fontcolor|#FFF|Regional Lymph Nodes (N)}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |N0 | |||
| style="padding: 5px 5px; background: #F5F5F5;" |No cancer in regional lymph nodes | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |N1-3 | |||
| style="padding: 5px 5px; background: #F5F5F5;" |There is cancer in the regional lymph nodes | |||
|- | |||
| style="padding: 0 5px; background: #4479BA" colspan=3 |{{fontcolor|#FFF| Distant Metastasis (M)}} | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |M0 | |||
| style="padding: 5px 5px; background: #F5F5F5;" |No distant [[metastasis]] | |||
|- | |||
| style="padding: 5px 5px; background: #DCDCDC;" |M1 | |||
| style="padding: 5px 5px; background: #F5F5F5;" |Distant metastasis | |||
|} | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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{{WS}} | {{WS}} | ||
[[Category: | [[Category:Oncology]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Hematology]] | |||
[[Category:Immunology]] |
Latest revision as of 19:07, 18 December 2017
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2], Ahmed Younes M.B.B.CH [3]
MALT lymphoma Microchapters |
Diagnosis |
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Treatment |
Case Studies |
MALT lymphoma staging On the Web |
American Roentgen Ray Society Images of MALT lymphoma staging |
Overview
The staging of MALT lymphoma is based on two staging systems: Ann Arbor staging system and the TNM staging system.[1]
Staging
The staging of MALT lymphoma is based on two staging systems: Ann Arbor staging system and the TNM staging system.[1]
Ann Arbor Staging System
The Ann Arbor staging system has been modified for gastric MALT lymphoma.[1]
Stage | Description |
---|---|
Stage I |
Tumor is confined to the stomach without spread to the lymph nodes |
Stage II |
Tumor extends into the abdomen and has spread to the lymph nodes
|
Stage IIE |
Tumor penetrates the serosa to spread to adjacent organs or tissues |
Stage IV |
Disseminated spread to extranodal sites or spread to the lymph nodes above the diaphragm (supradiaphragmatic nodal involvement) |
TNM Staging System
The TNM staging system for stomach cancer has also been applied to gastric MALT lymphoma. TNM stands for tumor, nodes, and metastasis.[1]
TNM Classification | Definition | |
---|---|---|
Primary Tumor (T) | ||
T1 | The lymphoma is confined to the mucosa or submucosa
| |
T2 | Lymphoma invades the muscularis propria | |
T3 | Lymphoma penetrates the subserosa | |
T4 | Lymphoma has grown through the serosa or invades organs near the stomach | |
T1a | Tumor invades subepithelial connective tissue, but has no lymphovascular invasion | |
T1b | Tumor invades subepithelial connective tissue and has spread to the lymphatic channels or blood vessels | |
T2 | Tumor invades the erectile tissue (corpus spongiosum or cavernosum) | |
Regional Lymph Nodes (N) | ||
N0 | No cancer in regional lymph nodes | |
N1-3 | There is cancer in the regional lymph nodes | |
Distant Metastasis (M) | ||
M0 | No distant metastasis | |
M1 | Distant metastasis |
References
- ↑ 1.0 1.1 1.2 1.3 Staging MALT lymphoma of the stomach. Canadian Cancer Society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/non-hodgkin-lymphoma/types-of-nhl/malt-lymphoma/?region=on. Accessed on January 25, 2016