Leopard syndrome surgery: Difference between revisions

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==Surgical Therapy==
==Surgical Therapy==
For those who are disturbed by the appearance of lentigines, Cryosurgery may be beneficial.  Due to the large number of lentigines this may prove time consuming.  In case of cardiac anomalies        at diagnosis, a periodic assessment should be performed as recommended by the cardiologist.  Mild pulmonary valve stenosis has a good prognosis, while severe valvular dysplasia  may recommend valvulotomy or valvulectomy.<ref name="Limongelli-2007">{{Cite journal  | last1 = Limongelli | first1 = G. | last2 = Pacileo | first2 = G. | last3 = Marino | first3 = B. | last4 = Digilio | first4 = MC. | last5 = Sarkozy | first5 = A. | last6 = Elliott | first6 = P. | last7 = Versacci | first7 = P. | last8 = Calabro | first8 = P. | last9 = De Zorzi | first9 = A. | title = Prevalence and clinical significance of cardiovascular abnormalities in patients with the LEOPARD syndrome. | journal = Am J Cardiol | volume = 100 | issue = 4 | pages = 736-41 | month = Aug | year = 2007 | doi = 10.1016/j.amjcard.2007.03.093 | PMID = 17697839 }}</ref>
For those who are disturbed by the appearance of lentigines, Cryosurgery may be beneficial.  Due to the large number of lentigines this may prove time consuming.  In case of cardiac anomalies        at diagnosis, a periodic assessment should be performed as recommended by the cardiologist.  Mild [[pulmonary valve stenosis]] has a good prognosis, while severe valvular dysplasia  may recommend valvulotomy or valvulectomy.<ref name="Limongelli-2007">{{Cite journal  | last1 = Limongelli | first1 = G. | last2 = Pacileo | first2 = G. | last3 = Marino | first3 = B. | last4 = Digilio | first4 = MC. | last5 = Sarkozy | first5 = A. | last6 = Elliott | first6 = P. | last7 = Versacci | first7 = P. | last8 = Calabro | first8 = P. | last9 = De Zorzi | first9 = A. | title = Prevalence and clinical significance of cardiovascular abnormalities in patients with the LEOPARD syndrome. | journal = Am J Cardiol | volume = 100 | issue = 4 | pages = 736-41 | month = Aug | year = 2007 | doi = 10.1016/j.amjcard.2007.03.093 | PMID = 17697839 }}</ref>


==References==
==References==

Revision as of 17:11, 5 September 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Surgical Therapy

For those who are disturbed by the appearance of lentigines, Cryosurgery may be beneficial. Due to the large number of lentigines this may prove time consuming. In case of cardiac anomalies at diagnosis, a periodic assessment should be performed as recommended by the cardiologist. Mild pulmonary valve stenosis has a good prognosis, while severe valvular dysplasia may recommend valvulotomy or valvulectomy.[1]

References

  1. Limongelli, G.; Pacileo, G.; Marino, B.; Digilio, MC.; Sarkozy, A.; Elliott, P.; Versacci, P.; Calabro, P.; De Zorzi, A. (2007). "Prevalence and clinical significance of cardiovascular abnormalities in patients with the LEOPARD syndrome". Am J Cardiol. 100 (4): 736–41. doi:10.1016/j.amjcard.2007.03.093. PMID 17697839. Unknown parameter |month= ignored (help)

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