Lactic acidosis pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Pathophysiology
- Lactic acidosis occurs when cells make lactic acid faster than it can be metabolized. [1] [2]
Lactic acidosis is an underlying process in the development of rigor mortis. Tissue in the muscles of the deceased resort to anaerobic metabolism in the absence of oxygen and significant amounts of lactic acid are released into the muscle tissue. This along with the loss of ATP causes the muscles to grow stiff.