Lactic acidosis

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Lactic acidosis
Lactic acid

Lactic acidosis Microchapters

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Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Lactic acidosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

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Laboratory Findings

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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Lactate levels raised (plasma or serum); lactic acidemia; lactic acidaemia.

Overview

Lactic acid is a carbohydrate and its levels rise with increased metabolism during exercise and with catecholamine stimulation. The excess of lactic acid in the body causes muscle pain and serum levels above 4mmol/L are defined as lactic acidosis.

Historical Perspective


Classification


Pathophysiology


Causes


Differentiating Lactic acidosis from other Diseases


Epidemiology and Demographics


Risk Factors


Natural History, Complications and Prognosis


Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings


Treatment

Medical Therapy | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies


Case Studies

Case #1


Related Chapters


Additional Resources

  • Clinical Physiology of Acid-Base and Electrolyte Disorders by Rose, Post
  • Intensive Care Medicine by Irwin and Rippe
  • The ICU Book by Marino
  • Cohen R, Woods H. Clinical and Biochemical Aspects of Lactic Acidosis. Blackwell Scientific Publications; 1976. ISBN 0-632-09460-5.

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