LNX1

Ligand of numb-protein X 1
Identifiers
Symbols	LNX1 ; MPDZ; LNX; PDZRN2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 7819
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Ligand of numb-protein X 1, also known as LNX1, is a human gene.

Further reading

• Dho SE, Jacob S, Wolting CD; et al. (1998). "The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX". J. Biol. Chem. 273 (15): 9179–87. PMID 9535908.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xie Y, Zhao W, Wang W; et al. (2002). "Identification of a human LNX protein containing multiple PDZ domains". Biochem. Genet. 39 (3–4): 117–26. PMID 11521506.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nie J, McGill MA, Dermer M; et al. (2002). "LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation". EMBO J. 21 (1–2): 93–102. doi:10.1093/emboj/21.1.93. PMID 11782429.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rice DS, Northcutt GM, Kurschner C (2002). "The Lnx family proteins function as molecular scaffolds for Numb family proteins". Mol. Cell. Neurosci. 18 (5): 525–40. doi:10.1006/mcne.2001.1024. PMID 11922143.CS1 maint: Multiple names: authors list (link)
• Sollerbrant K, Raschperger E, Mirza M; et al. (2003). "The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX)". J. Biol. Chem. 278 (9): 7439–44. doi:10.1074/jbc.M205927200. PMID 12468544.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Clark HF, Gurney AL, Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Katoh M, Katoh M (2004). "Identification and characterization of PDZRN3 and PDZRN4 genes in silico". Int. J. Mol. Med. 13 (4): 607–13. PMID 15010864.
• Armbruester V, Sauter M, Roemer K; et al. (2004). "Np9 protein of human endogenous retrovirus K interacts with ligand of numb protein X.". J. Virol. 78 (19): 10310–9. doi:10.1128/JVI.78.19.10310-10319.2004. PMID 15367597.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen J, Xu J, Zhao W; et al. (2005). "Characterization of human LNX, a novel ligand of Numb protein X that is downregulated in human gliomas". Int. J. Biochem. Cell Biol. 37 (11): 2273–83. doi:10.1016/j.biocel.2005.02.028. PMID 16002321.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lim J, Hao T, Shaw C; et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weiss A, Baumgartner M, Radziwill G; et al. (2007). "c-Src is a PDZ interaction partner and substrate of the E3 ubiquitin ligase Ligand-of-Numb protein X1". FEBS Lett. 581 (26): 5131–6. doi:10.1016/j.febslet.2007.09.062. PMID 17936276.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)