KHSRP

KH-type splicing regulatory protein (FUSE binding protein 2)
File:PBB Protein KHSRP image.jpg PDB rendering based on 2hh2.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2hh2​, 2hh3​
Identifiers
Symbols	KHSRP ; FBP2; FUBP2; KSRP; MGC99676
External IDs	Template:OMIM5 HomoloGene: 2734
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE KHSRP 204371 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

KH-type splicing regulatory protein (FUSE binding protein 2), also known as KHSRP, is a human gene.

Further reading

• Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. PMID 1602151.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.CS1 maint: Multiple names: authors list (link)
• Davis-Smyth T, Duncan RC, Zheng T; et al. (1997). "The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators". J. Biol. Chem. 271 (49): 31679–87. PMID 8940189.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Min H, Turck CW, Nikolic JM, Black DL (1997). "A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer". Genes Dev. 11 (8): 1023–36. PMID 9136930.CS1 maint: Multiple names: authors list (link)
• Chou MY, Rooke N, Turck CW, Black DL (1999). "hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells". Mol. Cell. Biol. 19 (1): 69–77. PMID 9858532.CS1 maint: Multiple names: authors list (link)
• Ring HZ, Vameghi-Meyers V, Nikolic JM; et al. (1999). "Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17". Genomics. 56 (3): 350–2. doi:10.1006/geno.1998.5725. PMID 10087204.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lellek H, Kirsten R, Diehl I; et al. (2000). "Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex". J. Biol. Chem. 275 (26): 19848–56. doi:10.1074/jbc.M001786200. PMID 10781591.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chou MY, Underwood JG, Nikolic J; et al. (2000). "Multisite RNA binding and release of polypyrimidine tract binding protein during the regulation of c-src neural-specific splicing". Mol. Cell. 5 (6): 949–57. PMID 10911989.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Markovtsov V, Nikolic JM, Goldman JA; et al. (2000). "Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein". Mol. Cell. Biol. 20 (20): 7463–79. PMID 11003644.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chen CY, Gherzi R, Ong SE; et al. (2002). "AU binding proteins recruit the exosome to degrade ARE-containing mRNAs". Cell. 107 (4): 451–64. PMID 11719186.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hall MP, Huang S, Black DL (2004). "Differentiation-induced colocalization of the KH-type splicing regulatory protein with polypyrimidine tract binding protein and the c-src pre-mRNA". Mol. Biol. Cell. 15 (2): 774–86. doi:10.1091/mbc.E03-09-0692. PMID 14657238.CS1 maint: Multiple names: authors list (link)
• Gherzi R, Lee KY, Briata P; et al. (2004). "A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery". Mol. Cell. 14 (5): 571–83. doi:10.1016/j.molcel.2004.05.002. PMID 15175153.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Suswam EA, Nabors LB, Huang Y; et al. (2005). "IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR". Int. J. Cancer. 113 (6): 911–9. doi:10.1002/ijc.20675. PMID 15514971.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wickham L, Benjannet S, Marcinkiewicz E; et al. (2005). "Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin". J. Neurochem. 92 (1): 93–102. doi:10.1111/j.1471-4159.2004.02840.x. PMID 15606899.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chou CF, Mulky A, Maitra S; et al. (2006). "Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay". Mol. Cell. Biol. 26 (10): 3695–706. doi:10.1128/MCB.26.10.3695-3706.2006. PMID 16648466.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Villén J, Gerber SA; et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gherzi R, Trabucchi M, Ponassi M; et al. (2007). "The RNA-binding protein KSRP promotes decay of beta-catenin mRNA and is inactivated by PI3K-AKT signaling". PLoS Biol. 5 (1): e5. doi:10.1371/journal.pbio.0050005. PMID 17177604.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)