Ischemic stroke MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2]

Overview

MRI

MRI diffusion weighted imaging

MR diffusion weighted imaging is the most sensitive and specific test for diagnosing ischemic stroke and may help detect presence of infarction in few minutes of onset of symptoms. It may also help differentiate viable tissue from infarct area if combined with MR perfusion. For diagnosing ischemic stroke in the emergency setting, MRI scan has the sensitivity and specificity of 83% and 98% respectively.[1] MRI scan is superior to CT scan for being more sensitive and specific in detection of lacunar and posterior fossa infarcts, differentiation between acute and chronic stroke and detection of microbleeds. Another additional advantage is absence of ionising radiation compared to CT scan. Some of the disadvantages of MRI scan may include lack of availability in acute setting, higher cost, inability to use it in patients with metallic implants. MRI with contrast cannot be used in patients with renal failure.[2][3]

MRI perfusion weighted imaging

May help determine the diagnosis, selection of patients and time window for thrombolytic therapy and to determine the prognosis in ischemic stroke. It uses contrast material to give an insight into the perfusion of cerebral tissues by blood and may help measure cerebral blood flow volume and transit time, thus helping determine infarct area and penumbra.[3][4][5]

For AHA/ASA guidelines for other imaging studies in patients with ischemic stroke, please click here

Patient No 1: Change in Mental Status (Images courtesy of RadsWiki)

Patient No 2: Left ACA Infarction




References

  1. Chalela, J (2007). "Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison". Lancet. 369 (9558): 293–8. PMID 17258669. Retrieved 2008-01-22. Unknown parameter |coauthors= ignored (help)
  2. Wintermark M, Sanelli PC, Albers GW, Bello J, Derdeyn C, Hetts SW; et al. (2013). "Imaging recommendations for acute stroke and transient ischemic attack patients: A joint statement by the American Society of Neuroradiology, the American College of Radiology, and the Society of NeuroInterventional Surgery". AJNR Am J Neuroradiol. 34 (11): E117–27. doi:10.3174/ajnr.A3690. PMC 4072500. PMID 23907247.
  3. 3.0 3.1 Leiva-Salinas C, Wintermark M (2010). "Imaging of acute ischemic stroke". Neuroimaging Clin N Am. 20 (4): 455–68. doi:10.1016/j.nic.2010.07.002. PMC 2965616. PMID 20974371.
  4. https://radiopaedia.org/articles/mr-perfusion-weighted-imaging-1 Accessed on November 17, 2016
  5. Copen WA, Schaefer PW, Wu O (2011). "MR perfusion imaging in acute ischemic stroke". Neuroimaging Clin N Am. 21 (2): 259–83, x. doi:10.1016/j.nic.2011.02.007. PMC 3135980. PMID 21640299.


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