Iron deficiency anemia other diagnostic studies: Difference between revisions

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{{Iron deficiency anemia}}
{{Iron deficiency anemia}}
{{CMG}}; {{AE}} {{JSS}}


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==Overview==
 
Bone marrow aspiration, colonoscopy and upper GI endoscopy can be done to look for the cause of iron deficiency anemia.
{{CMG}}


==Other Diagnostic Studies==
==Other Diagnostic Studies==
===Bone Marrow Aspiration===
===Bone Marrow Aspiration===
Conventionally, a definitive diagnosis requires a demonstration of depleted body iron stores obtained by [[bone marrow aspiration]], with the marrow stained for iron.<ref>{{cite journal |last=Mazza |first=J. |coauthors=Barr, R. M.; McDonald, J. W.; and Valberg, L. S.;
A definitive diagnosis requires a demonstration of depleted body iron stores obtained by [[bone marrow aspiration]], with the marrow stained for iron.<ref>{{cite journal |last=Mazza |first=J. |coauthors=Barr, R. M.; McDonald, J. W.; and Valberg, L. S.;
|date=21 October 1978|title=Usefulness of the serum ferritin concentration in the detection of iron deficiency in a general hospital |journal=Canadian Medical Association Journal |volume=119 |issue=8 |pages=884–886 |url=http://www.cmaj.ca/cgi/content/abstract/119/8/884 |accessdate=2009-05-04 |pmid=737638 |pmc=1819106 }}</ref><ref>{{cite journal |last=Kis |first=AM |coauthors=Carnes, M |year=1998 |month=July |title=Detecting Iron Deficiency in Anemic Patients with Concomitant Medical Problems |journal=J Gen Intern Med. |volume=13 |issue=7 |pages=455–61 |pmid=9686711 |doi=10.1046/j.1525-1497.1998.00134.x |pmc=1496985 }}</ref> Because this is invasive and painful, while a [[clinical trial]] of iron supplementation is inexpensive and not traumatic, patients are often treated based on clinical history and serum ferritin levels without a bone marrow biopsy. Furthermore, a study published April 2009<ref>{{cite journal |last=Thomason |first=Ronald W. |coauthors=Almiski, Muhamad S. |year=2009 |month=April |title=Evidence That Stainable Bone Marrow Iron Following Parenteral Iron Therapy Does Not Correlate With Serum Iron Studies and May Not Represent Readily Available Storage Iron |journal=American Journal of Clinical Pathology |volume=131 |pages=580–585 |url=http://ajcp.ascpjournals.org/content/131/4/580.full |accessdate=2009-05-04 |doi=10.1309/AJCPBAY9KRZF8NUC |pmid=19289594 |issue=4 }}</ref> questions the value of stainable bone marrow iron following parenteral iron therapy.
|date=21 October 1978|title=Usefulness of the serum ferritin concentration in the detection of iron deficiency in a general hospital |journal=Canadian Medical Association Journal |volume=119 |issue=8 |pages=884–886 |url=http://www.cmaj.ca/cgi/content/abstract/119/8/884 |accessdate=2009-05-04 |pmid=737638 |pmc=1819106 }}</ref><ref>{{cite journal |last=Kis |first=AM |coauthors=Carnes, M |year=1998 |month=July |title=Detecting Iron Deficiency in Anemic Patients with Concomitant Medical Problems |journal=J Gen Intern Med. |volume=13 |issue=7 |pages=455–61 |pmid=9686711 |doi=10.1046/j.1525-1497.1998.00134.x |pmc=1496985 }}</ref>  


===[[Colonoscopy]]===
===[[Colonoscopy]]===
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==References==
==References==
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{{reflist|2}}
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[[Category:Needs content]]
[[Category:Disease]]
[[Category:Hematology]]
[[Category:Hematology]]
[[Category:Malnutrition]]
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:primary care]]
[[Category:Endocrinology]]
[[Category:Needs overview]]
{{WH}}
{{WS}}

Latest revision as of 22:25, 29 July 2020

Iron deficiency anemia Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Jogeet Singh Sekhon, M.D. [2]

Overview

Bone marrow aspiration, colonoscopy and upper GI endoscopy can be done to look for the cause of iron deficiency anemia.

Other Diagnostic Studies

Bone Marrow Aspiration

A definitive diagnosis requires a demonstration of depleted body iron stores obtained by bone marrow aspiration, with the marrow stained for iron.[1][2]

Colonoscopy

May be done to look for the cause of iron deficiency:

  • Celiac disease
  • Crohn's disease

Upper Endoscopy

May be done to look for the site of bleeding.

References

  1. Mazza, J. (21 October 1978). "Usefulness of the serum ferritin concentration in the detection of iron deficiency in a general hospital". Canadian Medical Association Journal. 119 (8): 884–886. PMC 1819106. PMID 737638. Retrieved 2009-05-04. Unknown parameter |coauthors= ignored (help)
  2. Kis, AM (1998). "Detecting Iron Deficiency in Anemic Patients with Concomitant Medical Problems". J Gen Intern Med. 13 (7): 455–61. doi:10.1046/j.1525-1497.1998.00134.x. PMC 1496985. PMID 9686711. Unknown parameter |coauthors= ignored (help); Unknown parameter |month= ignored (help)

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