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==Medical Therapy==
==Medical Therapy==
* The blood glucose can be raised to normal within minutes by taking (or receiving) 10-20 grams of [[carbohydrate]]. It can be taken as food or drink if the person is conscious and able to swallow. This amount of carbohydrate is contained in about 3-4 ounces (100-120 ml) of orange, apple, or grape juice, about 4-5 ounces (120-150 ml) of regular (non-diet) soda, about one slice of bread, about 4 crackers, or about 1 serving of most starchy foods. [[Starch]] is quickly digested to glucose (unless the person is taking [[acarbose]]), but adding fat or protein retards digestion. Symptoms should begin to improve within 5 minutes, though full recovery may take 10-20 minutes. Overfeeding does not speed recovery and if the person has diabetes will simply produce hyperglycemia afterwards.
==='''Asymptomatic''' ===
* Cases with blood glucose of ≤70 mg/dL with regular monitoring.
* Repeating the measurement in short time
* Avoiding critical tasks
* Ingesting carbohydrates
* adjusting the regimen to avoid other attacks.


* If a person is suffering such severe effects of hypoglycemia that they cannot (due to combativeness) or should not (due to seizures or unconsciousness) be given anything by mouth, glucose can be given by intravenous infusion or the glucose can be rapidly raised by an injection of [[glucagon]]. Further details of [[glucagon]] use are provided in the article on [[diabetic hypoglycemia]].
=== '''Symptomatic''' ===
* Patients should have source of carbohydrates available all times.
* 20 grams is usually sufficient to raise the blood glucose.
* In patients taking alpha-glucosidase inhibitor (acarbose), only dextrose should be used to treat hypoglycemia becuase acarbose slowes digestion of carbohydrates.


* One situation where starch may be less effective than glucose or sucrose is when a person is taking acarbose. Since [[acarbose]] and other [[alpha-glucosidase inhibitor]]s prevents starch and other sugars from being broken down into [[monosaccharide]]s that can be absorbed by the body, patients taking these medications should consume monosaccharide-containing foods such as glucose tablets, honey, or juice to reverse hypoglycemia.
=== '''Severe''' ===
* A subcutaneous or intramuscular injection of 0.5 to 1.0 mg of glucagon will correct hypoglycemia within 15 minutes.
* If failed this attempt or in severe cases, 25% or 50% dextrose intravenously (IV) followed by subcutaneous glucose.
* If these measures aren't available:
* Squeezing a glucose gel in the space between the teeth and buccal mucosa with patient head tilted on side to prevent aspiration.
* If glucose gel isn't available, putting table sugar under the tongue may save patient.  [57,58]


* Hypoglycemia due to hormone deficiencies such as [[hypopituitarism]] or [[adrenal insufficiency]] usually ceases when the appropriate hormone is replaced.
* Hypoglycemia due to hormone deficiencies such as [[hypopituitarism]] or [[adrenal insufficiency]] usually ceases when the appropriate hormone is replaced.
 
* Patients with diabetes history who has loss of consciousness and there is no method to determine nature of coma; hypoglycemi or hyperglycemia,then glucose should be given empirically. This will correct hypoglycemia and will not be particularly dangerous if blood glucose concentration is high.
===Contraindicated medications===
{{MedCondContrAbs
 
|MedCond = Hypoglycemia|Insulin aspart|Insulin glulisine|Insulin lispro}}


==References==
==References==

Revision as of 15:56, 14 July 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Medical Therapy

Asymptomatic 

  • Cases with blood glucose of ≤70 mg/dL with regular monitoring.
  • Repeating the measurement in short time
  • Avoiding critical tasks
  • Ingesting carbohydrates
  • adjusting the regimen to avoid other attacks.

Symptomatic

  • Patients should have source of carbohydrates available all times.
  • 20 grams is usually sufficient to raise the blood glucose.
  • In patients taking alpha-glucosidase inhibitor (acarbose), only dextrose should be used to treat hypoglycemia becuase acarbose slowes digestion of carbohydrates.

Severe 

  • A subcutaneous or intramuscular injection of 0.5 to 1.0 mg of glucagon will correct hypoglycemia within 15 minutes.
  • If failed this attempt or in severe cases, 25% or 50% dextrose intravenously (IV) followed by subcutaneous glucose.
  • If these measures aren't available:
  • Squeezing a glucose gel in the space between the teeth and buccal mucosa with patient head tilted on side to prevent aspiration.
  • If glucose gel isn't available, putting table sugar under the tongue may save patient. [57,58]
  • Hypoglycemia due to hormone deficiencies such as hypopituitarism or adrenal insufficiency usually ceases when the appropriate hormone is replaced.
  • Patients with diabetes history who has loss of consciousness and there is no method to determine nature of coma; hypoglycemi or hyperglycemia,then glucose should be given empirically. This will correct hypoglycemia and will not be particularly dangerous if blood glucose concentration is high.

References


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