Hereditary nonpolyposis colorectal cancer physical examination: Difference between revisions
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==Overview== | ==Overview== | ||
Patients with hereditary nonpolyposis colorectal cancer usually appear healthy. Physical examination of patients with | Patients with hereditary nonpolyposis colorectal cancer usually appear healthy. Physical examination of patients with hereditary nonpolyposis colorectal cancer may show the presence of the fordyce granules.<ref name="pmid15879014">{{cite journal |vauthors=De Felice C, Parrini S, Chitano G, Gentile M, Dipaola L, Latini G |title=Fordyce granules and hereditary non-polyposis colorectal cancer syndrome |journal=Gut |volume=54 |issue=9 |pages=1279–82 |year=2005 |pmid=15879014 |pmc=1774669 |doi=10.1136/gut.2005.064881 |url=}}</ref> | ||
==Physical Examination== | ==Physical Examination== |
Revision as of 21:38, 9 February 2016
Hereditary Nonpolyposis Colorectal Cancer Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Patients with hereditary nonpolyposis colorectal cancer usually appear healthy. Physical examination of patients with hereditary nonpolyposis colorectal cancer may show the presence of the fordyce granules.[1]
Physical Examination
General Appearance
- Patients are usually well-appearing
- Pale
- Emaciated
Vital Signs
Vital signs are generally within normal limits, but patients with severe disease may have the following vital signs:
- Low-grade fever
- Tachyapnea
- Tachycardia
- Low blood pressure
Abdomen
- Discomfort on palpation
- Hepatomegaly
- Ascites
Chest
- Decreased/absent breath sounds
Skin
- Pallor
- Fordyce granules (FGs): Oral ectopic sebaceous glands and alteration in vascular patterns in the oral mucosa
HEENT
Extremities
- Swelling of hands and feet
Gallery
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Extraoral photograph image showing Fordyce granules in the upper lip (arrows) of individual III:5 with hereditary nonpolyposis colorectal cancer and colorectal cancer.Creative Commons BY-SA-NC[2]
References
- ↑ De Felice C, Parrini S, Chitano G, Gentile M, Dipaola L, Latini G (2005). "Fordyce granules and hereditary non-polyposis colorectal cancer syndrome". Gut. 54 (9): 1279–82. doi:10.1136/gut.2005.064881. PMC 1774669. PMID 15879014.
- ↑ Almeida FT, Gomes RR, Leite AF, Sousa JB, Acevedo AC, Guerra EN. Oral manifestations of hereditary nonpolyposis colorectal cancer syndrome: a family case series. J Med Case Rep. 2014;8:249.