Hereditary nonpolyposis colorectal cancer: Difference between revisions

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__NOTOC__
'''For patient information, click [[Hereditary nonpolyposis colorectal cancer (patient information)|here]]'''
'''For patient information, click [[Hereditary nonpolyposis colorectal cancer (patient information)|here]]'''
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{{Hereditary nonpolyposis colorectal cancer}}
{{Hereditary nonpolyposis colorectal cancer}}
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{{CMG}}{{AE}}{{MV}}{{Akram}}


'''''Synonyms and Keywords:''''' Lynch syndrome; HNPCC
'''''Synonyms and Keywords:''''' Lynch syndrome; HNPCC; Hereditary non-polyposis colorectal carcinoma; Lynch II syndrome; Lynch I syndrome; Familial nonpolyposis colon cancer; Hereditary nonpolyposis colorectal neoplasms


==[[Hereditary nonpolyposis colorectal cancer overview|Overview]]==
==[[Hereditary nonpolyposis colorectal cancer overview|Overview]]==
==[[Hereditary nonpolyposis colorectal cancer historical perspective|Historical Perspective]]==


==[[Hereditary nonpolyposis colorectal cancer classification|Classification]]==
==[[Hereditary nonpolyposis colorectal cancer classification|Classification]]==


==[[Hereditary nonpolyposis colorectal cancer historical perspective|Historical Perspective]]==
==[[Hereditary nonpolyposis colorectal cancer pathophysiology|Pathophysiology]]==
 
==[[Hereditary nonpolyposis colorectal cancer causes|Causes]]==


==[[Hereditary nonpolyposis colorectal cancer pathophysiology|Pathophysiology]]==
==[[Hereditary nonpolyposis colorectal cancer differential diagnosis|Differentiating Hereditary Nonpolyposis Colorectal Cancer from Other Diseases]]==
[[Hereditary nonpolyposis colorectal cancer pathophysiology#Characteristics of HNPCC-associated colon cancers|Characteristics of HNPCC-associated colon cancers]] | [[Hereditary nonpolyposis colorectal cancer pathophysiology#Genetic basis of Lynch syndrome|Genetic basis of Lynch syndrome]]


==[[Hereditary nonpolyposis colorectal cancer epidemiology and demographics|Epidemiology & Demographics]]==
==[[Hereditary nonpolyposis colorectal cancer epidemiology and demographics|Epidemiology and Demographics]]==


==[[Hereditary nonpolyposis colorectal cancer epidemiology and demographics|Risk Factors]]==
==[[Hereditary nonpolyposis colorectal cancer epidemiology and demographics|Risk Factors]]==


==[[Hereditary nonpolyposis colorectal cancer screening|Screening]]==
==[[Hereditary nonpolyposis colorectal cancer screening|Screening]]==
[[Hereditary nonpolyposis colorectal cancer screening#|Screening strategy]] | [[Hereditary nonpolyposis colorectal cancer screening#Amsterdam criteria|Amsterdam criteria]]
==[[Hereditary nonpolyposis colorectal cancer causes|Causes]]==


==[[Hereditary nonpolyposis colorectal cancer differential diagnosis|Differentiating Hereditary nonpolyposis colorectal cancer from other Diseases]]==
==[[Hereditary nonpolyposis colorectal cancer natural history|Natural History, Complications and Prognosis]]==
 
==[[Hereditary nonpolyposis colorectal cancer natural history|Natural History, Complications & Prognosis]]==
[[Hereditary nonpolyposis colorectal cancer natural history#Malignant consequences of the Lynch syndrome|Malignant consequences of the Lynch syndrome]]


==Diagnosis==
==Diagnosis==
[[Hereditary nonpolyposis colorectal cancer history and symptoms|History & Symptoms]] | [[Hereditary nonpolyposis colorectal cancer physical examination|Physical Examination]] | [[Hereditary nonpolyposis colorectal cancer staging|Staging]] | [[Hereditary nonpolyposis colorectal cancer laboratory tests|Lab Tests]] | [[Hereditary nonpolyposis colorectal cancer electrocardiogram|Electrocardiogram]] | [[Hereditary nonpolyposis colorectal cancer chest x ray|Chest X Ray]] | [[Hereditary nonpolyposis colorectal cancer CT|CT]] | [[Hereditary nonpolyposis colorectal cancer MRI|MRI]] | [[Hereditary nonpolyposis colorectal cancer echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Hereditary nonpolyposis colorectal cancer other imaging findings|Other Imaging Findings]] | [[Hereditary nonpolyposis colorectal cancer other diagnostic studies#Genetic testing|Genetic testing]]
[[Hereditary nonpolyposis colorectal cancer staging|Staging]] | [[Hereditary nonpolyposis colorectal cancer history and symptoms|History and Symptoms]] | [[Hereditary nonpolyposis colorectal cancer physical examination|Physical Examination]] | [[Hereditary nonpolyposis colorectal cancer laboratory tests|Laboratory Findings ]] | [[Hereditary nonpolyposis colorectal cancer chest x ray|Chest X Ray]] | [[Hereditary nonpolyposis colorectal cancer CT|CT]] | [[Hereditary nonpolyposis colorectal cancer MRI|MRI]] | [[Hereditary nonpolyposis colorectal cancer ultrasound|Ultrasound]] | [[Hereditary nonpolyposis colorectal cancer other imaging findings|Other Imaging Findings]] | [[Hereditary nonpolyposis colorectal cancer other diagnostic studies|Other diagnostic studies]]


==Treatment==
==Treatment==
[[Hereditary nonpolyposis colorectal cancer medical therapy|Medical Therapy]] | [[Hereditary nonpolyposis colorectal cancer surgery|Surgery]] | [[Hereditary nonpolyposis colorectal cancer primary prevention|Primary Prevention]] | [[Hereditary nonpolyposis colorectal cancer secondary prevention|Secondary Prevention]]  
[[Hereditary nonpolyposis colorectal cancer medical therapy|Medical Therapy]] | [[Hereditary nonpolyposis colorectal cancer surgery|Surgery]] | [[Hereditary nonpolyposis colorectal cancer primary prevention|Primary Prevention]] | [[Hereditary nonpolyposis colorectal cancer secondary prevention|Secondary Prevention]] | [[Hereditary nonpolyposis colorectal cancer cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Hereditary nonpolyposis colorectal cancer future or investigational therapies|Future or Investigational Therapies]]


==Resources==
* [http://siadat.info/hnpcc.htm Sample histology slides of HNPCC at siadat.info]
* [http://siadat.info/hnpcc.htm#hnpcc03 Aberrant Cytokeratin 20 expression in HNPCC at siadat.info]
* [http://siadat.info/hnpcc.htm#hnpcc04 Aberrant Cytokeratin 7 expression in HNPCC at siadat.info]
* [http://ghr.nlm.nih.gov/condition=hereditarynonpolyposiscolorectalcancer FAQs on HNPCC] from the [[National Institute of Health]]
* {{GeneTests|hnpcc}}
* [http://www.annalsnyas.org/cgi/content/abstract/910/1/62 Pathology of Hereditary Nonpolyposis Colorectal Cancer at annalsnyas.org]
[[de:Hereditäres non-polypöses kolorektales Karzinom]]
[[pl:Zespół Lyncha]]


[[Category:Disease]]
[[Category:Disease]]
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Latest revision as of 22:33, 28 January 2019

For patient information, click here

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]Ali Akram, M.B.B.S.[3]

Synonyms and Keywords: Lynch syndrome; HNPCC; Hereditary non-polyposis colorectal carcinoma; Lynch II syndrome; Lynch I syndrome; Familial nonpolyposis colon cancer; Hereditary nonpolyposis colorectal neoplasms

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hereditary Nonpolyposis Colorectal Cancer from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging | History and Symptoms | Physical Examination | Laboratory Findings | Chest X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other diagnostic studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies


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