Hepatocellular carcinoma risk factors: Difference between revisions

Jump to navigation Jump to search
m (Bot: Removing from Primary care)
 
(12 intermediate revisions by 3 users not shown)
Line 5: Line 5:


==Overview==
==Overview==
Common risk factors in the development of hepatocellular carcinoma are [[chronic hepatitis B]], [[chronic hepatitis C]], [[cirrhosis]], and inherited metabolic diseases.
Common [[risk factors]] in the development of hepatocellular carcinoma are [[chronic hepatitis B]] [[infection]], [[chronic hepatitis C]] [[infection]], [[cirrhosis]], inherited [[metabolic diseases]] and [[Aflatoxins|aflaoxins]].


==Common Risk Factors==
==Common Risk Factors==
Common risk factors that may increase the risk of developing hepatocellular carcinoma are:<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/types/liver/hp/adult-liver-treatment-pdq</ref><ref name="pmid22021666">{{cite journal |vauthors=Trichopoulos D, Bamia C, Lagiou P, Fedirko V, Trepo E, Jenab M, Pischon T, Nöthlings U, Overved K, Tjønneland A, Outzen M, Clavel-Chapelon F, Kaaks R, Lukanova A, Boeing H, Aleksandrova K, Benetou V, Zylis D, Palli D, Pala V, Panico S, Tumino R, Sacerdote C, Bueno-De-Mesquita HB, Van Kranen HJ, Peeters PH, Lund E, Quirós JR, González CA, Sanchez Perez MJ, Navarro C, Dorronsoro M, Barricarte A, Lindkvist B, Regnér S, Werner M, Hallmans G, Khaw KT, Wareham N, Key T, Romieu I, Chuang SC, Murphy N, Boffetta P, Trichopoulou A, Riboli E |title=Hepatocellular carcinoma risk factors and disease burden in a European cohort: a nested case-control study |journal=J. Natl. Cancer Inst. |volume=103 |issue=22 |pages=1686–95 |year=2011 |pmid=22021666 |pmc=3216968 |doi=10.1093/jnci/djr395 |url=}}</ref><ref>Cecil, Russell L., James B. Wyngaarden, and Lloyd H. Smith. ''Textbook of ''. Philadelphia: Saunders, 1988. Print.</ref><ref name="urlRedirecting">{{cite web |url=https://doi.org/10.1053/j.gastro.2004.09.010 |title=Redirecting |format= |work= |accessdate=}}</ref>
Common [[risk factors]] that may increase the risk of developing hepatocellular carcinoma are:<ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/types/liver/hp/adult-liver-treatment-pdq</ref><ref name="pmid22021666">{{cite journal |vauthors=Trichopoulos D, Bamia C, Lagiou P, Fedirko V, Trepo E, Jenab M, Pischon T, Nöthlings U, Overved K, Tjønneland A, Outzen M, Clavel-Chapelon F, Kaaks R, Lukanova A, Boeing H, Aleksandrova K, Benetou V, Zylis D, Palli D, Pala V, Panico S, Tumino R, Sacerdote C, Bueno-De-Mesquita HB, Van Kranen HJ, Peeters PH, Lund E, Quirós JR, González CA, Sanchez Perez MJ, Navarro C, Dorronsoro M, Barricarte A, Lindkvist B, Regnér S, Werner M, Hallmans G, Khaw KT, Wareham N, Key T, Romieu I, Chuang SC, Murphy N, Boffetta P, Trichopoulou A, Riboli E |title=Hepatocellular carcinoma risk factors and disease burden in a European cohort: a nested case-control study |journal=J. Natl. Cancer Inst. |volume=103 |issue=22 |pages=1686–95 |year=2011 |pmid=22021666 |pmc=3216968 |doi=10.1093/jnci/djr395 |url=}}</ref><ref>Cecil, Russell L., James B. Wyngaarden, and Lloyd H. Smith. ''Textbook of ''. Philadelphia: Saunders, 1988. Print.</ref><ref name="urlRedirecting">{{cite web |url=https://doi.org/10.1053/j.gastro.2004.09.010 |title=Redirecting |format= |work= |accessdate=}}</ref><ref name="CHEDIDKRUEL2017">{{cite journal|last1=CHEDID|first1=Marcio F.|last2=KRUEL|first2=Cleber R. P.|last3=PINTO|first3=Marcelo A.|last4=GREZZANA-FILHO|first4=Tomaz J. M.|last5=LEIPNITZ|first5=Ian|last6=KRUEL|first6=Cleber D. P.|last7=SCAFFARO|first7=Leandro A.|last8=CHEDID|first8=Aljamir D.|title=HEPATOCELLULAR CARCINOMA: DIAGNOSIS AND OPERATIVE MANAGEMENT|journal=ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)|volume=30|issue=4|year=2017|pages=272–278|issn=2317-6326|doi=10.1590/0102-6720201700040011}}</ref><ref name="pmid28989095">{{cite journal |vauthors=Fujiwara N, Friedman SL, Goossens N, Hoshida Y |title=Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine |journal=J. Hepatol. |volume= |issue= |pages= |year=2017 |pmid=28989095 |doi=10.1016/j.jhep.2017.09.016 |url=}}</ref><ref name="TradBibani2017">{{cite journal|last1=Trad|first1=Dorra|last2=Bibani|first2=Norsaf|last3=Sabbah|first3=Meriam|last4=Elloumi|first4=Hela|last5=Gargouri|first5=Dalila|last6=Ouakaa|first6=Asma|last7=Kharrat|first7=Jamel|title=Known, new and emerging risk factors of hepatocellular carcinoma (review)|journal=La Presse Médicale|volume=46|issue=11|year=2017|pages=1000–1007|issn=07554982|doi=10.1016/j.lpm.2017.09.025}}</ref><ref name="pmid28987047">{{cite journal |vauthors=Budny A, Kozłowski P, Kamińska M, Jankiewicz M, Kolak A, Budny B, Budny W, Niemunis-Sawicka J, Szczypiór G, Kurniawka B, Burdan F |title=[Epidemiology and risk factors of hepatocellular carcinoma] |language=Polish |journal=Pol. Merkur. Lekarski |volume=43 |issue=255 |pages=133–139 |year=2017 |pmid=28987047 |doi= |url=}}</ref><ref name="Parkin2006">{{cite journal|last1=Parkin|first1=Donald Maxwell|title=The global health burden of infection-associated cancers in the year 2002|journal=International Journal of Cancer|volume=118|issue=12|year=2006|pages=3030–3044|issn=0020-7136|doi=10.1002/ijc.21731}}</ref><ref name="ShiZhu2005">{{cite journal|last1=Shi|first1=J|last2=Zhu|first2=L|last3=Liu|first3=S|last4=Xie|first4=W-f|title=A meta-analysis of case–control studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma in China|journal=British Journal of Cancer|volume=92|issue=3|year=2005|pages=607–612|issn=0007-0920|doi=10.1038/sj.bjc.6602333}}</ref>
*[[Chronic hepatitis B]]
*[[Chronic hepatitis B]]
*[[Chronic hepatitis C]]  
*[[Chronic hepatitis C]]  
*[[Cirrhosis]] with [[hemochromatosis]]   
*[[Cirrhosis]] with [[hemochromatosis]]   
*[[Nonalcoholic steatohepatitis]]
*[[Nonalcoholic steatohepatitis]]
*Food infected with [[Aspergillus flavus]] (especially [[Peanut|peanuts]] and corns stored during prolonged wet seasons), which produces [[Aflatoxin|aflatoxins]].
*Food contaminated with [[Aspergillus flavus]] (especially [[Peanut|peanuts]] and corns stored during prolonged wet seasons), which produces [[aflatoxins]].


==Less Common Risk Factors==
==Less Common Risk Factors==
Less common risk factors that may increase the risk of developing hepatocellular carcinoma are:<ref name="pmid9762169">{{cite journal |vauthors=Clavière C, Bronowicki JP, Hudziak H, Bigard MA, Gaucher P |title=[Role of sex steroids and their receptors in the pathophysiology of hepatocellular carcinoma] |language=French |journal=Gastroenterol. Clin. Biol. |volume=22 |issue=1 |pages=73–86 |year=1998 |pmid=9762169 |doi= |url=}}</ref><ref name="urlStudies of Cancer in Humans - Tobacco Smoke and Involuntary Smoking - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK316397/#p6b-s2.4 |title=Studies of Cancer in Humans - Tobacco Smoke and Involuntary Smoking - NCBI Bookshelf |format= |work= |accessdate=}}</ref><ref name="pmid15285078">{{cite journal |vauthors= |title=Tobacco smoke and involuntary smoking |journal=IARC Monogr Eval Carcinog Risks Hum |volume=83 |issue= |pages=1–1438 |year=2004 |pmid=15285078 |pmc=4781536 |doi= |url=}}</ref>
Less common [[risk factors]] that may increase the risk of developing hepatocellular carcinoma are:<ref name="TradBibani20172">{{cite journal|last1=Trad|first1=Dorra|last2=Bibani|first2=Norsaf|last3=Sabbah|first3=Meriam|last4=Elloumi|first4=Hela|last5=Gargouri|first5=Dalila|last6=Ouakaa|first6=Asma|last7=Kharrat|first7=Jamel|title=Known, new and emerging risk factors of hepatocellular carcinoma (review)|journal=La Presse Médicale|volume=46|issue=11|year=2017|pages=1000–1007|issn=07554982|doi=10.1016/j.lpm.2017.09.025}}</ref><ref name="pmid9762169">{{cite journal |vauthors=Clavière C, Bronowicki JP, Hudziak H, Bigard MA, Gaucher P |title=[Role of sex steroids and their receptors in the pathophysiology of hepatocellular carcinoma] |language=French |journal=Gastroenterol. Clin. Biol. |volume=22 |issue=1 |pages=73–86 |year=1998 |pmid=9762169 |doi= |url=}}</ref><ref name="urlStudies of Cancer in Humans - Tobacco Smoke and Involuntary Smoking - NCBI Bookshelf">{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK316397/#p6b-s2.4 |title=Studies of Cancer in Humans - Tobacco Smoke and Involuntary Smoking - NCBI Bookshelf |format= |work= |accessdate=}}</ref><ref name="pmid15285078">{{cite journal |vauthors= |title=Tobacco smoke and involuntary smoking |journal=IARC Monogr Eval Carcinog Risks Hum |volume=83 |issue= |pages=1–1438 |year=2004 |pmid=15285078 |pmc=4781536 |doi= |url=}}</ref>
*[[Anabolic steroids]]  
*[[Anabolic steroids]]  
*[[alpha1-antitrypsin deficiency]]  
*[[Alpha 1-antitrypsin deficiency|Alpha1-antitrypsin deficiency]]  
*[[Arsenic]]  
*[[Arsenic]]  
*[[Alcohol]]
*[[Alcohol]]
Line 24: Line 24:
*[[Diabetes Mellitus]]
*[[Diabetes Mellitus]]
*Food infected with [[Aspergillus flavus]] (especially [[peanut]]s and corns stored during prolonged wet seasons), which produces [[aflatoxin]].
*Food infected with [[Aspergillus flavus]] (especially [[peanut]]s and corns stored during prolonged wet seasons), which produces [[aflatoxin]].
*[[glycogen storage diseases]]
*[[Glycogen storage diseases]]
*[[hemochromatosis]]
*[[Hemochromatosis]]
*Inherited metabolic diseases such as:
*[[Inherited]] [[metabolic diseases]] such as:
*[[porphyria cutanea tarda]]
**[[Porphyria cutanea tarda]]
*[[Smoking]]
*[[Smoking]]
*[[tyrosinemia]]
*[[Tyrosinemia]]
*[[Vinyl chloride]] and thorium dioxide
*[[Vinyl chloride]] and [[thorium dioxide]]
*[[Wilson disease]]
*[[Wilson disease]]


Line 40: Line 40:


[[Category:Disease]]
[[Category:Disease]]
[[Category:Medicine]]
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Up-To-Date]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Hepatology]]
[[Category:Hepatology]]
[[Category:Gastroenterology]]
[[Category:Surgery]]
[[Category:Surgery]]
[[Category:Emergency medicine]]

Latest revision as of 22:08, 29 July 2020

Hepatocellular carcinoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes of Hepatocellular carcinoma

Differentiating Hepatocellular carcinoma from other Diseases

Epidemiology & Demographics

Risk Factors

Screening

Natural History, Complications & Prognosis

Diagnosis

Diagnostic study of choice

History and symptoms

Physical Examination

Lab Tests

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Hepatocellular carcinoma risk factors On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Hepatocellular carcinoma risk factors

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Hepatocellular carcinoma risk factors

CDC on Hepatocellular carcinoma risk factors

Hepatocellular carcinoma risk factors in the news

Blogs on Hepatocellular carcinoma risk factors

Directions to Hospitals Treating Hepatocellular carcinoma

Risk calculators and risk factors for Hepatocellular carcinoma risk factors

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2] Mohamad Alkateb, MBBCh [3]

Overview

Common risk factors in the development of hepatocellular carcinoma are chronic hepatitis B infection, chronic hepatitis C infection, cirrhosis, inherited metabolic diseases and aflaoxins.

Common Risk Factors

Common risk factors that may increase the risk of developing hepatocellular carcinoma are:[1][2][3][4][5][6][7][8][9][10]

Less Common Risk Factors

Less common risk factors that may increase the risk of developing hepatocellular carcinoma are:[11][12][13][14]

References

  1. National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/types/liver/hp/adult-liver-treatment-pdq
  2. Trichopoulos D, Bamia C, Lagiou P, Fedirko V, Trepo E, Jenab M, Pischon T, Nöthlings U, Overved K, Tjønneland A, Outzen M, Clavel-Chapelon F, Kaaks R, Lukanova A, Boeing H, Aleksandrova K, Benetou V, Zylis D, Palli D, Pala V, Panico S, Tumino R, Sacerdote C, Bueno-De-Mesquita HB, Van Kranen HJ, Peeters PH, Lund E, Quirós JR, González CA, Sanchez Perez MJ, Navarro C, Dorronsoro M, Barricarte A, Lindkvist B, Regnér S, Werner M, Hallmans G, Khaw KT, Wareham N, Key T, Romieu I, Chuang SC, Murphy N, Boffetta P, Trichopoulou A, Riboli E (2011). "Hepatocellular carcinoma risk factors and disease burden in a European cohort: a nested case-control study". J. Natl. Cancer Inst. 103 (22): 1686–95. doi:10.1093/jnci/djr395. PMC 3216968. PMID 22021666.
  3. Cecil, Russell L., James B. Wyngaarden, and Lloyd H. Smith. Textbook of . Philadelphia: Saunders, 1988. Print.
  4. "Redirecting".
  5. CHEDID, Marcio F.; KRUEL, Cleber R. P.; PINTO, Marcelo A.; GREZZANA-FILHO, Tomaz J. M.; LEIPNITZ, Ian; KRUEL, Cleber D. P.; SCAFFARO, Leandro A.; CHEDID, Aljamir D. (2017). "HEPATOCELLULAR CARCINOMA: DIAGNOSIS AND OPERATIVE MANAGEMENT". ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo). 30 (4): 272–278. doi:10.1590/0102-6720201700040011. ISSN 2317-6326.
  6. Fujiwara N, Friedman SL, Goossens N, Hoshida Y (2017). "Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine". J. Hepatol. doi:10.1016/j.jhep.2017.09.016. PMID 28989095.
  7. Trad, Dorra; Bibani, Norsaf; Sabbah, Meriam; Elloumi, Hela; Gargouri, Dalila; Ouakaa, Asma; Kharrat, Jamel (2017). "Known, new and emerging risk factors of hepatocellular carcinoma (review)". La Presse Médicale. 46 (11): 1000–1007. doi:10.1016/j.lpm.2017.09.025. ISSN 0755-4982.
  8. Budny A, Kozłowski P, Kamińska M, Jankiewicz M, Kolak A, Budny B, Budny W, Niemunis-Sawicka J, Szczypiór G, Kurniawka B, Burdan F (2017). "[Epidemiology and risk factors of hepatocellular carcinoma]". Pol. Merkur. Lekarski (in Polish). 43 (255): 133–139. PMID 28987047.
  9. Parkin, Donald Maxwell (2006). "The global health burden of infection-associated cancers in the year 2002". International Journal of Cancer. 118 (12): 3030–3044. doi:10.1002/ijc.21731. ISSN 0020-7136.
  10. Shi, J; Zhu, L; Liu, S; Xie, W-f (2005). "A meta-analysis of case–control studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma in China". British Journal of Cancer. 92 (3): 607–612. doi:10.1038/sj.bjc.6602333. ISSN 0007-0920.
  11. Trad, Dorra; Bibani, Norsaf; Sabbah, Meriam; Elloumi, Hela; Gargouri, Dalila; Ouakaa, Asma; Kharrat, Jamel (2017). "Known, new and emerging risk factors of hepatocellular carcinoma (review)". La Presse Médicale. 46 (11): 1000–1007. doi:10.1016/j.lpm.2017.09.025. ISSN 0755-4982.
  12. Clavière C, Bronowicki JP, Hudziak H, Bigard MA, Gaucher P (1998). "[Role of sex steroids and their receptors in the pathophysiology of hepatocellular carcinoma]". Gastroenterol. Clin. Biol. (in French). 22 (1): 73–86. PMID 9762169.
  13. "Studies of Cancer in Humans - Tobacco Smoke and Involuntary Smoking - NCBI Bookshelf".
  14. "Tobacco smoke and involuntary smoking". IARC Monogr Eval Carcinog Risks Hum. 83: 1–1438. 2004. PMC 4781536. PMID 15285078.


Template:WikiDoc Sources