Hepatocellular adenoma differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Hepatocellular adenoma must be differentiated from other diseases such as hepatocellular carcinoma (HCC), focal nodular hyperplasia (FNH), liver metastases (hypervascular), haemangioma of the liver, fibrolamellar hepatocellular carcinoma.[1]
Hepatocellular adenoma differential diagnosis
Radiological differential diagnosis
Hepatocellular adenoma must be differentiated from other diseases such as:
- Hepatocellular carcinoma (HCC)[1]
- Washout tends to leave the lesion hypointense c.f. to rest of liver
- Rim enhancement of pseudocapsule may persist on delayed scan
- Different demographics
- May be difficult to distinguish if well differentiated
- Fibrolamellar hepatocellular carcinoma
- Radiating/central scar
- Calcification more common
- Lymph node enlargement common
- Focal nodular hyperplasia (FNH)
- T2: bright central scars that have late enhancement
- US: may be difficult to differentiate adenoma from FNH on nonenhanced ultrasound
- Liver metastases (hypervascular)
- Usually hypointense on T1, and moderately hyperintense on T2
- Fat and haemorrhage are less common
- Haemangioma of the liver
References
- ↑ 1.0 1.1 Radiopaedia 2015 Hepatic adenoma>"Radiopedia 2015 Hepatic adenoma [Dr Matt A. Morgan and Dr Koshy Jacob]".