Hepatocellular adenoma causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]
Overview
Estrogen has a central role in the development of hepatocellular adenoma. The causes of hepatocellular adenoma can include the settings where prolonged and/or excessive estrogen exposure is involved. These can include oral contraceptive medications, pregnancy, long term use of anabolic androgenic steroids, metabolic syndrome, obesity, glycogen storage diseases, and clomiphene.
Causes
- Estrogen has a central role in the development of hepatocellular adenoma.
- The causes of hepatocellular adenoma can include the settings involving prolonged and/or excessive estrogen exposure, such as:[1][2][3][4][5][6][7][8][9]
References
- ↑ M. Kawakatsu, V. Vilgrain, S. Erlinger & H. Nahum (1997). "Disappearance of liver cell adenoma: CT and MR imaging". Abdominal imaging. 22 (3): 274–276. PMID 9107649. Unknown parameter
|month=ignored (help) - ↑ W. H. Marks, N. Thompson & H. Appleman (1988). "Failure of hepatic adenomas (HCA) to regress after discontinuance of oral contraceptives. An association with focal nodular hyperplasia (FNH) and uterine leiomyoma". Annals of surgery. 208 (2): 190–195. PMID 2840865. Unknown parameter
|month=ignored (help)</ref<ref>H. Tesluk & J. Lawrie (1981). "Hepatocellular adenoma. Its transformation to carcinoma in a user of oral contraceptives". Archives of pathology & laboratory medicine. 105 (6): 296–299. PMID 6263214. Unknown parameter|month=ignored (help) - ↑ D. Carrasco, M. Barrachina, M. Prieto & J. Berenguer (1984). "Clomiphene citrate and liver-cell adenoma". The New England journal of medicine. 310 (17): 1120–1121. doi:10.1056/NEJM198404263101716. PMID 6323982. Unknown parameter
|month=ignored (help) - ↑ G. B. Coombes, J. Reiser, F. J. Paradinas & I. Burn (1978). "An androgen-associated hepatic adenoma in a trans-sexual". The British journal of surgery. 65 (12): 869–870. PMID 737424. Unknown parameter
|month=ignored (help) - ↑ U. Beuers, W. O. Richter, M. M. Ritter, B. Wiebecke & P. Schwandt (1991). "Klinefelter's syndrome and liver adenoma". Journal of clinical gastroenterology. 13 (2): 214–216. PMID 1851773. Unknown parameter
|month=ignored (help) - ↑ N. S. Alshak, J. Cocjin, L. Podesta, R. van de Velde, L. Makowka, P. Rosenthal & S. A. Geller (1994). "Hepatocellular adenoma in glycogen storage disease type IV". Archives of pathology & laboratory medicine. 118 (1): 88–91. PMID 8285839. Unknown parameter
|month=ignored (help) - ↑ P. Labrune, P. Trioche, I. Duvaltier, P. Chevalier & M. Odievre (1997). "Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature". Journal of pediatric gastroenterology and nutrition. 24 (3): 276–279. PMID 9138172. Unknown parameter
|month=ignored (help) - ↑ S. Bala, P. H. Wunsch & W. G. Ballhausen (1997). "Childhood hepatocellular adenoma in familial adenomatous polyposis: mutations in adenomatous polyposis coli gene and p53". Gastroenterology. 112 (3): 919–922. PMID 9041254. Unknown parameter
|month=ignored (help) - ↑ J. K. Baum, J. J. Bookstein, F. Holtz & E. W. Klein (1973). "Possible association between benign hepatomas and oral contraceptives". Lancet (London, England). 2 (7835): 926–929. PMID 4126557. Unknown parameter
|month=ignored (help)