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{{Gonadoblastoma}}
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==Overview==
{{SK}} [[Gonadoblastomas]]; [[Gonadoblastomata]]
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==Overview==
A '''gonadoblastoma''' is a complex [[neoplasm]] composed of a mixture of [[gonad]]al elements, such as large primordial [[germ cell]]s, immature [[Sertoli cell]]s or [[granulosa cell]]s of the [[sex cord]], and gonadal [[stromal cell]]s.


==Associations==
Gonadoblastoma is most often associated with abnormal chromosomal [[karyotype]], gonadal [[dysgenesis]], and the presence of a [[Y chromosome]].


It has been found in association with [[Turner's syndrome]].<ref name="pmid17947845">{{cite journal |author=Maggio MC, Liotta A, De Grazia E, Cimador M, Di Pace R, Corsello G |title=Polycystic ovary and gonadoblastoma in Turner's syndrome |journal=Minerva Pediatr. |volume=59 |issue=4 |pages=397–401 |year=2007 |pmid=17947845 |doi=}}</ref><ref name="pmid17128558">{{cite journal |author=Bianco B, Lipay MV, Melaragno MI, Guedes AD, Verreschi IT |title=Detection of hidden Y mosaicism in Turner's syndrome: importance in the prevention of gonadoblastoma |journal=J. Pediatr. Endocrinol. Metab. |volume=19 |issue=9 |pages=1113–7 |year=2006 |pmid=17128558 |doi=}}</ref>
==[[Gonadoblastoma overview|Overview]]==


==Classification==
==[[Gonadoblastoma historical perspective|Historical Perspective]]==
{{main|Germ cell tumor}}
Gonadoblastoma is classified as a [[germ cell tumor]].


Formerly, gonadoblastoma was sometimes regarded as a subset of [[dysgerminoma]]. In modern literature, it is sometimes considered to progress to dysgerminoma.<ref name="pmid17454768">{{cite journal |author=Cooper C, Cooper M, Carter J, Russell P |title=Gonadoblastoma progressing to dysgerminoma in a 55-year-old woman with normal karyotype |journal=Pathology |volume=39 |issue=2 |pages=284–5 |year=2007 |pmid=17454768 |doi=10.1080/00313020701230708}}</ref>
==[[Gonadoblastoma classification|Classification]]==


==References==
==[[Gonadoblastoma pathophysiology|Pathophysiology]]==
{{reflist|2}}


==External links==
==[[Gonadoblastoma causes|Causes]]==
*[http://www.health.am/cr/testis-non-germ-cell-tumors/ www.health.am: Gonadoblastoma]


{{SIB}}
==[[Gonadoblastoma differential diagnosis|Differentiating Gonadoblastoma from other Diseases]]==
{{Tumors}}
 
{{Soft tissue tumors and sarcomas}}
==[[Gonadoblastoma epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Gonadoblastoma risk factors|Risk Factors]]==
 
==[[Gonadoblastoma screening|Screening]]==
 
==[[Gonadoblastoma natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==Diagnosis==
[[Gonadoblastoma diagnostic study of choice|Diagnostic study of choice]] | [[Gonadoblastoma history and symptoms|History and Symptoms]] | [[Gonadoblastoma physical examination|Physical Examination]] | [[Gonadoblastoma laboratory findings|Laboratory Findings]] | [[Gonadoblastoma electrocardiogram|Electrocardiogram]] | [[Gonadoblastoma x ray|X-Ray Findings]] | [[Gonadoblastoma echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Gonadoblastoma CT scan|CT-Scan Findings]] | [[Gonadoblastoma MRI|MRI Findings]] | [[Gonadoblastoma other imaging findings|Other Imaging Findings]] | [[Gonadoblastoma other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
[[Gonadoblastoma medical therapy|Medical Therapy]] | [[Gonadoblastoma surgery|Surgery]] | [[Gonadoblastoma primary prevention|Primary Prevention]] | [[Gonadoblastoma secondary prevention|Secondary Prevention]] | [[Gonadoblastoma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Gonadoblastoma future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
[[Gonadoblastoma case study one|Case #1]]
 
 
[[Category:Medicine]]


[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Gynecology]]
[[Category:Gynecology]]
[[Category:Proctology]]
[[Category:Up-To-Date]]
[[Category:Types of cancer]]
 
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Latest revision as of 06:33, 28 July 2020

Gonadoblastoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Gonadoblastoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]

Synonyms and keywords: Gonadoblastomas; Gonadoblastomata


Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Gonadoblastoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray Findings | Echocardiography and Ultrasound | CT-Scan Findings | MRI Findings | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1