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* '''Low-grade''' gliomas are well-differentiated (not anaplastic);  these are [[cancer|benign]] and portend a better prognosis for the patient.   
* '''Low-grade''' gliomas are well-differentiated (not anaplastic);  these are [[cancer|benign]] and portend a better prognosis for the patient.   
* '''High-grade''' gliomas are undifferentiated or [[anaplastic]];  these are [[cancer|malignant]] and carry a worse prognosis.   
* '''High-grade''' gliomas are undifferentiated or [[anaplastic]];  these are [[cancer|malignant]] and carry a worse prognosis.   
Of numerous grading systems in use, the most common is the [[World Health Organization]] (WHO) grading system for astrocytoma.  The WHO system assigns a grade from 1 to 4, with 1 being the least aggressive and 4 being the most aggressive.  Various types of astrocytomas are given corresponding WHO grades.
:'''WHO grading system for astrocytomas'''
:*WHO Grade 1 — e.g., [[pilocytic astrocytoma]]
:*WHO Grade 2 — e.g., diffuse or low-grade astrocytoma
:*WHO Grade 3 — e.g., [[anaplastic]] ([[cancer|malignant]]) astrocytoma
:*WHO Grade 4 — [[glioblastoma multiforme]] (most common glioma in adults)
The prognosis is the worst for grade 4 gliomas, with an average survival time of 12 months. Overall, few patients survive beyond 3 years. [http://www.emedicine.com/NEURO/topic147.htm]
[http://www.cjns.org/25augtoc/long.html]


===By location===
===By location===

Revision as of 18:02, 21 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Classification

By type of cell

Gliomas are named according to the specific type of cell they most closely resemble. The main types of gliomas are:

By grade

Gliomas are further categorized according to their grade, which is determined by pathologic evaluation of the tumor.

  • Low-grade gliomas are well-differentiated (not anaplastic); these are benign and portend a better prognosis for the patient.
  • High-grade gliomas are undifferentiated or anaplastic; these are malignant and carry a worse prognosis.

By location

The gliomas can also be roughly classified according to their location:

References


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