Glioma classification: Difference between revisions

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{{Glioma}}  
{{Glioma}}  
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}{{SR}}
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}}, {{SR}}


==Overview==
==Overview==
Glioma may be classified into several subtypes based on the type of cell, grade, and location.<ref name=ddd>Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref>
Glioma may be classified into several subtypes based on the type of cell (ependymoma, astrocytoma, oligodendroglioma, and mixed gliomas), grade (low-grade and high-grade gliomas), and location (infratentorial and supratentorial).<ref name=ddd>Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref>


==Classification==
==Classification==
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* [[Astrocytoma]]s — [[astrocyte]]s
* [[Astrocytoma]]s — [[astrocyte]]s
* [[Oligodendroglioma]]s — [[oligodendrocyte]]s
* [[Oligodendroglioma]]s — [[oligodendrocyte]]s
* Mixed gliomas, such as [[oligoastrocytomas]], contain cells from different types of [[glia]].
* Mixed gliomas ([[oligoastrocytomas]]) — cells from different types of [[glia]]


===2. Based on the grade===
===2. Based on the grade===
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'''WHO grading system for astrocytomas'''
'''WHO grading system for astrocytomas'''
*WHO Grade 1 &mdash; e.g., [[pilocytic astrocytoma]]  
 
*WHO Grade 2 &mdash; e.g., low-grade astrocytoma
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
*WHO Grade 3 &mdash; e.g., [[anaplastic]] ([[cancer|malignant]]) astrocytoma
|valign=top|
*WHO Grade 4 &mdash; e.g., [[glioblastoma multiforme]]
|+
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Grade}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|Type of tumor}}
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
WHO grade 1
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Pilocytic astrocytoma]]
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
WHO grade 2
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Astrocytoma|Low-grade astrocytoma]]
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
WHO grade 3
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[anaplastic|Anaplastic astrocytoma]]
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
WHO grade 4
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Glioblastoma multiforme]]
|}


===3. Based on the location===
===3. Based on the location===
Glioma may be classified according to the location into two subtypes:<ref name=ddd>Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref>
Glioma may be classified according to the location into two subtypes:<ref name=ddd>Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma</ref>
* [[Infratentorial]] : mostly in children (70%)
* [[Infratentorial]]: mostly in children (70%)
* [[Supratentorial]] : mostly in adults (70%)
* [[Supratentorial]]: mostly in adults (70%)


==References==
==References==
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Latest revision as of 23:37, 26 November 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2], Sujit Routray, M.D. [3]

Overview

Glioma may be classified into several subtypes based on the type of cell (ependymoma, astrocytoma, oligodendroglioma, and mixed gliomas), grade (low-grade and high-grade gliomas), and location (infratentorial and supratentorial).[1]

Classification

Glioma may be classified into several subtypes based on the type of cell, grade, and location.[1]

1. Based on the type of cell

Glioma may be classified according to the type of cell into four subtypes:[1]

2. Based on the grade

Glioma may be classified according to the grade into two subtypes:[1]

  • Low-grade gliomas are well-differentiated tumors. These are benign tumors.
  • High-grade gliomas are undifferentiated or anaplastic tumors. These are malignant tumors.

WHO grading system for astrocytomas

Grade Type of tumor

WHO grade 1

WHO grade 2

WHO grade 3

WHO grade 4

3. Based on the location

Glioma may be classified according to the location into two subtypes:[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 Classification of glioma. Wikipedia. https://en.wikipedia.org/wiki/Glioma


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