Glaucoma overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Glaucoma is a group of diseases of the optic nerve involving loss of retinal ganglion cells in a characteristic pattern of optic neuropathy. Although raised intraocular pressure is a significant risk factor for developing glaucoma, there is no set threshold for intraocular pressure that causes glaucoma. One person may develop nerve damage at a relatively low pressure, while another person may have high eye pressure for years and yet never develop damage. Untreated glaucoma leads to permanent damage of the optic nerve and resultant visual field loss, which can progress to blindness.

Glaucoma has been nicknamed "the silent sight thief".[1] Worldwide, it is the second leading cause of blindness.[2] Glaucoma affects one in two hundred people aged fifty and younger and one in ten over the age of eighty.

Human eye cross-sectional view. Courtesy NIH National Eye Institute
  1. "Glaucoma." Centre for Vision Research. Accessed October 17, 2006.
  2. "Glaucoma, Normal Tension, Susceptibility To." OMIM - Online Mendelian Inheritance in Man. Accessed October 17, 2006.