Gestational trophoblastic neoplasia natural history, complications and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
* The prognosis for cure of patients with GTDs is good even when the disease has spread to distant organs, especially when only the lungs are involved.<ref name= abc> General Information About Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq Accessed on October 14, 2015</ref> | * The prognosis for cure of patients with GTDs is good even when the disease has spread to distant organs, especially when only the [[lungs]] are involved.<ref name= abc> General Information About Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq Accessed on October 14, 2015</ref> | ||
* The probability of cure depends on the following: | * The probability of cure depends on the following: | ||
:* [[Histologic]] type (invasive mole or choriocarcinoma) | :* [[Histologic]] type (invasive mole or choriocarcinoma) | ||
Revision as of 14:45, 19 October 2015
Template:Choriocarcinoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2]
Overview
Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as good.[1]
Natural history
- Patient has early symptoms like vaginal bleeding, passing of tissue resembling a “bunch of grapes” from the vagina, the abdomen may grow at a much faster rate than with a normal pregnancy
- nausea and vomiting, and absent fetal movement during pregnancy.
- As the tumor grows larger, patient may notice symptoms like lump in the vagina, hemoptysis, chest pain, trouble breathing, headache, dizziness, jaundice, paralysis, seizure, dysarthria, and dysphasia.
Prognosis
- The prognosis for cure of patients with GTDs is good even when the disease has spread to distant organs, especially when only the lungs are involved.[1]
- The probability of cure depends on the following:
- Histologic type (invasive mole or choriocarcinoma)
- Extent of spread of the disease/largest tumor size
- Level of serum beta-hCG
- Duration of disease from the initial pregnancy event to start of treatment
- Number and specific sites of metastasis
- Nature of antecedent pregnancy
- Extent of prior treatment
Complications
- Recurrence
- Anemia
References
- ↑ 1.0 1.1 General Information About Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq Accessed on October 14, 2015