Gestational trophoblastic neoplasia natural history, complications and prognosis: Difference between revisions

Revision as of 20:32, 14 October 2015

Patient has early symptoms like vaginal bleeding, passing of tissue resembling a “bunch of grapes” from the vagina, the abdomen may grow at a much faster rate than with a normal pregnancy
nausea and vomiting, and absent fetal movement during pregnancy.
As the tumor grows larger, patient may notice symptoms like lump in the vagina, hemoptysis, chest pain, trouble breathing, headache, dizziness, jaundice, paralysis, seizure, dysarthria, and dysphasia.

The prognosis for cure of patients with GTDs is good even when the disease has spread to distant organs, especially when only the lungs are involved.^[1]
The probability of cure depends on the following:

↑ General Information About Gestational Trophoblastic Disease. National Cancer Institute. http://www.cancer.gov/types/gestational-trophoblastic/hp/gtd-treatment-pdq Accessed on October 14, 2015

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 ==Overview==
 ==Natural history==
-* Patient has early symptoms like [[vaginal bleeding]], Passing of  tissue resembling a “bunch of grapes” from the vagina, the abdomen may grow at a much faster rate than with a normal pregnancy
+* Patient has early symptoms like [[vaginal bleeding]], passing of tissue resembling a “bunch of grapes” from the vagina, the abdomen may grow at a much faster rate than with a normal pregnancy
 * [[nausea]] and [[vomiting]], and absent fetal movement during pregnancy.
-* As the tumor grows larger, patient may notice symptoms like unusual bleeding or discharge from the lesion, large mass on the vulva, [[dysuria]], and [[dyspareunia]].
+* As the tumor grows larger, patient may notice symptoms like  lump in the vagina, [[hemoptysis]], [[chest pain]], trouble breathing, [[headache]], [[dizziness]], [[jaundice]], [[paralysis]], [[seizure]], [[dysarthria]], and [[dysphasia]].
-* In advanced disease, [[metastasis|metastases]] may be present in the [[abdomen]] and [[lung]]s.
-* The patient may present with [[dyspnea]], [[cough]] with blood-stained sputum, persistent pain or discomfort in the chest, [[edema]] hands/feet, and [[inguinal]] [[lymphadenopathy]].
-* Once the cancer spreads to the other organs, it is most likely fatal.
 ==Prognosis==