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==Natural History, Complications and Prognosis==
==Natural History, Complications and Prognosis==
In the National Comorbidity Survey (2005), 58% of patients diagnosed with [[Clinical depression|major depression]] were found to have an anxiety disorder; among these patients, the rate of comorbidity with GAD was 17.2%, and with [[panic disorder]], 9.9%. Patients with a diagnosed anxiety disorder also had high rates of comorbid depression, including 22.4% of patients with [[social phobia]], 9.4% with [[agoraphobia]], and 2.3% with panic disorder. For many, the symptoms of both depression and anxiety are not severe enough (i.e. are subsyndromal) to justify a primary diagnosis of either major depressive disorder  (MDD) or an anxiety disorder.  
*In the National Comorbidity Survey (2005), 58% of patients diagnosed with [[Clinical depression|major depression]] were found to have an anxiety disorder; among these patients, the rate of comorbidity with GAD was 17.2%, and with [[panic disorder]], 9.9%.  
 
*Patients with a diagnosed anxiety disorder also had high rates of comorbid depression, including 22.4% of patients with [[social phobia]], 9.4% with [[agoraphobia]], and 2.3% with panic disorder.  
Patients can also be categorized as having mixed anxiety-depressive disorder, and they are at significantly increased risk of developing full-blown depression or anxiety. Appropriate treatment is necessary to alleviate symptoms and prevent the emergence of more serious disease.{{Fact|date=February 2007}}
**For many, the symptoms of both depression and anxiety are not severe enough (i.e. are subsyndromal) to justify a primary diagnosis of either major depressive disorder  (MDD) or an anxiety disorder.  
 
*Patients can also be categorized as having mixed anxiety-depressive disorder, and they are at significantly increased risk of developing full-blown depression or anxiety. Appropriate treatment is necessary to alleviate symptoms and prevent the emergence of more serious disease.{{Fact|date=February 2007}}
Accumulating evidence indicates that patients with comorbid depression and anxiety tend to have greater illness severity and a lower treatment response than those with either disorder alone.{{Fact|date=February 2007}} In addition, social function and quality of life are more greatly impaired.  
*Accumulating evidence indicates that patients with comorbid depression and anxiety tend to have greater illness severity and a lower treatment response than those with either disorder alone.{{Fact|date=February 2007}} In addition, social function and quality of life are more greatly impaired.  
 
**In addition to coexisting with depression, research shows that GAD often coexists with [[substance abuse]] or other conditions associated with [[Stress (medicine)|stress]], such as [[irritable bowel syndrome]].{{Fact|date=May 2007}}
In addition to coexisting with depression, research shows that GAD often coexists with [[substance abuse]] or other conditions associated with [[Stress (medicine)|stress]], such as [[irritable bowel syndrome]].{{Fact|date=May 2007}} Patients with physical symptoms such as [[insomnia]] or [[headache]]s should also tell their doctors about their feelings of worry and tension. This will help the patient's health care provider to recognize whether the person is suffering from GAD.
*Patients with physical symptoms such as [[insomnia]] or [[headache]]s should also tell their doctors about their feelings of worry and tension.  
 
**This will help the patient's health care provider to recognize whether the person is suffering from GAD.
*Approximately one-quarter of the patients with generalized anxiety disorder, will develop [[panic disorder]].
*Approximately one-quarter of the patients with generalized anxiety disorder, will develop [[panic disorder]].



Revision as of 17:32, 10 August 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Irfan Dotani

Natural History, Complications and Prognosis

  • In the National Comorbidity Survey (2005), 58% of patients diagnosed with major depression were found to have an anxiety disorder; among these patients, the rate of comorbidity with GAD was 17.2%, and with panic disorder, 9.9%.
  • Patients with a diagnosed anxiety disorder also had high rates of comorbid depression, including 22.4% of patients with social phobia, 9.4% with agoraphobia, and 2.3% with panic disorder.
    • For many, the symptoms of both depression and anxiety are not severe enough (i.e. are subsyndromal) to justify a primary diagnosis of either major depressive disorder (MDD) or an anxiety disorder.
  • Patients can also be categorized as having mixed anxiety-depressive disorder, and they are at significantly increased risk of developing full-blown depression or anxiety. Appropriate treatment is necessary to alleviate symptoms and prevent the emergence of more serious disease.[citation needed]
  • Accumulating evidence indicates that patients with comorbid depression and anxiety tend to have greater illness severity and a lower treatment response than those with either disorder alone.[citation needed] In addition, social function and quality of life are more greatly impaired.
  • Patients with physical symptoms such as insomnia or headaches should also tell their doctors about their feelings of worry and tension.
    • This will help the patient's health care provider to recognize whether the person is suffering from GAD.
  • Approximately one-quarter of the patients with generalized anxiety disorder, will develop panic disorder.

References