Gadodiamide

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Gadodiamide
File:Gadodiamide.png
File:Gadodiamide2.png
Clinical data
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration
i.v.
Legal status
Legal status
Pharmacokinetic data
Protein bindingnegligible
Metabolismnot metabolized
Elimination half-life77.8 minutes
Excretionrenal
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC16H28GdN5O9
Molar mass591.672g/mol

Gadodiamide is a gadolinium based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. It is commonly marketed under the trade name Omniscan.

Uses

Gadodiamide is used to visualize blood vessels during MRI procedures. The use of gadodiamide in these scans allows for the diagnosis of intracranial lesions or blood-brain barrier anomalies.[1] It is a high osmolarity contrast agent at 789 mOsmol per kg of water.

Gadolinium based agents may cause a toxic reaction known as NSF in patients with severe kidney problems.

References

  1. "Gadodiamide Drug Information". Drugs.com Professional. Micromedex. 9 January 2007. Retrieved 2007-2-19. Check date values in: |accessdate= (help)

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