GIT1

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G protein-coupled receptor kinase interactor 1
Identifiers
Symbols GIT1 ;
External IDs Template:OMIM5 Template:MGI HomoloGene32204
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

G protein-coupled receptor kinase interactor 1, also known as GIT1, is a human gene.[1]


References

  1. "Entrez Gene: GIT1 G protein-coupled receptor kinase interactor 1".

Further reading

  • Hoefen RJ, Berk BC (2006). "The multifunctional GIT family of proteins". J. Cell. Sci. 119 (Pt 8): 1469–75. doi:10.1242/jcs.02925. PMID 16598076.
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.
  • Premont RT, Claing A, Vitale N; et al. (1998). "beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein". Proc. Natl. Acad. Sci. U.S.A. 95 (24): 14082–7. PMID 9826657.
  • Premont RT, Claing A, Vitale N; et al. (2000). "The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing". J. Biol. Chem. 275 (29): 22373–80. PMID 10896954.
  • Zhao ZS, Manser E, Loo TH, Lim L (2000). "Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly". Mol. Cell. Biol. 20 (17): 6354–63. PMID 10938112.
  • Kawachi H, Fujikawa A, Maeda N, Noda M (2001). "Identification of GIT1/Cat-1 as a substrate molecule of protein tyrosine phosphatase zeta /beta by the yeast substrate-trapping system". Proc. Natl. Acad. Sci. U.S.A. 98 (12): 6593–8. doi:10.1073/pnas.041608698. PMID 11381105.
  • Manabe R, Kovalenko M, Webb DJ, Horwitz AR (2002). "GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration". J. Cell. Sci. 115 (Pt 7): 1497–510. PMID 11896197.
  • Nishiya N, Shirai T, Suzuki W, Nose K (2003). "Hic-5 interacts with GIT1 with a different binding mode from paxillin". J. Biochem. 132 (2): 279–89. PMID 12153727.
  • Kim S, Ko J, Shin H; et al. (2003). "The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo". J. Biol. Chem. 278 (8): 6291–300. doi:10.1074/jbc.M212287200. PMID 12473661.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Shin H, Wyszynski M, Huh KH; et al. (2003). "Association of the kinesin motor KIF1A with the multimodular protein liprin-alpha". J. Biol. Chem. 278 (13): 11393–401. doi:10.1074/jbc.M211874200. PMID 12522103.
  • Ko J, Kim S, Valtschanoff JG; et al. (2003). "Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting". J. Neurosci. 23 (5): 1667–77. PMID 12629171.
  • Zhang H, Webb DJ, Asmussen H, Horwitz AF (2003). "Synapse formation is regulated by the signaling adaptor GIT1". J. Cell Biol. 161 (1): 131–42. doi:10.1083/jcb.200211002. PMID 12695502.
  • Ko J, Na M, Kim S; et al. (2004). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". J. Biol. Chem. 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177.
  • Haendeler J, Yin G, Hojo Y; et al. (2004). "GIT1 mediates Src-dependent activation of phospholipase Cgamma by angiotensin II and epidermal growth factor". J. Biol. Chem. 278 (50): 49936–44. doi:10.1074/jbc.M307317200. PMID 14523024.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • van Nieuw Amerongen GP, Natarajan K, Yin G; et al. (2004). "GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions". Circ. Res. 94 (8): 1041–9. doi:10.1161/01.RES.0000125627.77235.0C. PMID 15016733.
  • Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
  • Goehler H, Lalowski M, Stelzl U; et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.

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