GCM2

Glial cells missing homolog 2 (Drosophila)
Identifiers
Symbols	GCM2 ; GCMB; hGCMb
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3490
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Glial cells missing homolog 2 (Drosophila), also known as GCM2, is a human gene.

The Drosophila 'glial cells missing' (gcm) gene is thought to act as a binary switch between neuronal and glial cell determination. The gcm protein and mammalian gcm homologs contain a conserved N-terminal gcm motif that has DNA-binding activity. See GCM1 (MIM 603715).[supplied by OMIM]

Further reading

• Kanemura Y, Hiraga S, Arita N; et al. (1999). "Isolation and expression analysis of a novel human homologue of the Drosophila glial cells missing (gcm) gene". FEBS Lett. 442 (2–3): 151–6. PMID 9928992.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kammerer M, Pirola B, Giglio S, Giangrande A (1999). "GCMB, a second human homolog of the fly glide/gcm gene". Cytogenet. Cell Genet. 84 (1–2): 43–7. PMID 10343099.CS1 maint: Multiple names: authors list (link)
• Correa P, Akerström G, Westin G (2002). "Underexpression of Gcm2, a master regulatory gene of parathyroid gland development, in adenomas of primary hyperparathyroidism". Clin. Endocrinol. (Oxf). 57 (4): 501–5. PMID 12354132.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mungall AJ, Palmer SA, Sims SK; et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Maret A, Bourdeau I, Ding C; et al. (2004). "Expression of GCMB by intrathymic parathyroid hormone-secreting adenomas indicates their parathyroid cell origin". J. Clin. Endocrinol. Metab. 89 (1): 8–12. PMID 14715818.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kebebew E, Peng M, Wong MG; et al. (2005). "GCMB gene, a master regulator of parathyroid gland development, expression, and regulation in hyperparathyroidism". Surgery. 136 (6): 1261–6. doi:10.1016/j.surg.2004.06.056. PMID 15657585.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Thomée C, Schubert SW, Parma J; et al. (2005). "GCMB mutation in familial isolated hypoparathyroidism with residual secretion of parathyroid hormone". J. Clin. Endocrinol. Metab. 90 (5): 2487–92. doi:10.1210/jc.2004-2450. PMID 15728199.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Baumber L, Tufarelli C, Patel S; et al. (2006). "Identification of a novel mutation disrupting the DNA binding activity of GCM2 in autosomal recessive familial isolated hypoparathyroidism". J. Med. Genet. 42 (5): 443–8. doi:10.1136/jmg.2004.026898. PMID 15863676.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)