Fibroma classification: Difference between revisions
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{{Fibroma}} | {{Fibroma}} | ||
{{CMG}} {{AE}}{{Simrat}} | {{CMG}} {{AE}} {{M.N}},{{Simrat}} | ||
==Overview== | ==Overview== | ||
There is no classification system established for fibroma. Based on the pathophysiology and location of the tumor, fibroma may be classified into hard fibroma, soft fibroma, [[angiofibroma]], [[cystic | There is no classification system established for fibroma. Based on the [[pathophysiology]] and location of the [[tumor]], fibroma may be classified into hard fibroma, soft fibroma, [[angiofibroma]], [[Cyst|cystic]] fibroma, [[chondromyxoid fibroma]], [[desmoplastic fibroma]], [[nonossifying fibroma]], [[ossifying fibroma]], nuchal fibroma, [[collagenous fibroma]], fibroma of [[tendon]] sheath, perifollicular fibroma, [[pleomorphic]] fibroma, [[uterine fibroma]], neurofibroma, and [[ovarian fibroma]].<ref name="wiki">fibroma. Wikipedia(2015) https://en.wikipedia.org/wiki/Fibroma Accessed on February 25, 2016</ref> | ||
==Classification== | ==Classification== | ||
Based on the pathophysiology and location of the tumor fibroma may be classified into the following types, which is shown below in a tabular form: <ref name="pmid26175813">{{cite journal |vauthors=Boujoual M, Hakimi I, Kouach J, Oukabli M, Moussaoui DR, Dehayni M |title=Large twisted ovarian fibroma in menopausal women: a case report |journal=Pan Afr Med J |volume=20 |issue= |pages=322 |date=2015 |pmid=26175813 |pmc=4491469 |doi=10.11604/pamj.2015.20.322.5998 |url=}}</ref><ref name="pmid27876070">{{cite journal |vauthors=Chen H, Liu Y, Shen LF, Jiang MJ, Yang ZF, Fang GP |title=Ovarian thecoma-fibroma groups: clinical and sonographic features with pathological comparison |journal=J Ovarian Res |volume=9 |issue=1 |pages=81 |date=November 2016 |pmid=27876070 |pmc=5120502 |doi=10.1186/s13048-016-0291-2 |url=}}</ref><ref name="pmid27770806">{{cite journal |vauthors=Matsuda K, Tateishi S, Akazawa Y, Kinoshita A, Yoshida S, Morisaki S, Fukushima A, Matsuwaki T, Yoshiura KI, Nakashima M |title=Rapid growth of mitotically active cellular fibroma of the ovary: a case report and review of the literature |journal=Diagn Pathol |volume=11 |issue=1 |pages=101 |date=October 2016 |pmid=27770806 |doi=10.1186/s13000-016-0554-7 |url=}}</ref> | Based on the [[pathophysiology]] and location of the [[tumor]] fibroma may be classified into the following types, which is shown below in a tabular form:<ref name="pmid26175813">{{cite journal |vauthors=Boujoual M, Hakimi I, Kouach J, Oukabli M, Moussaoui DR, Dehayni M |title=Large twisted ovarian fibroma in menopausal women: a case report |journal=Pan Afr Med J |volume=20 |issue= |pages=322 |date=2015 |pmid=26175813 |pmc=4491469 |doi=10.11604/pamj.2015.20.322.5998 |url=}}</ref><ref name="pmid27876070">{{cite journal |vauthors=Chen H, Liu Y, Shen LF, Jiang MJ, Yang ZF, Fang GP |title=Ovarian thecoma-fibroma groups: clinical and sonographic features with pathological comparison |journal=J Ovarian Res |volume=9 |issue=1 |pages=81 |date=November 2016 |pmid=27876070 |pmc=5120502 |doi=10.1186/s13048-016-0291-2 |url=}}</ref><ref name="pmid27770806">{{cite journal |vauthors=Matsuda K, Tateishi S, Akazawa Y, Kinoshita A, Yoshida S, Morisaki S, Fukushima A, Matsuwaki T, Yoshiura KI, Nakashima M |title=Rapid growth of mitotically active cellular fibroma of the ovary: a case report and review of the literature |journal=Diagn Pathol |volume=11 |issue=1 |pages=101 |date=October 2016 |pmid=27770806 |doi=10.1186/s13000-016-0554-7 |url=}}</ref> <ref name="pmid17907440">{{cite journal |vauthors=Takenaga RK, Frassica FJ, McCarthy EF |title=Subperiosteal chondromyxoid fibroma: a report of two cases |journal=Iowa Orthop J |volume=27 |issue= |pages=104–7 |date=2007 |pmid=17907440 |pmc=2150655 |doi= |url=}}</ref><ref name="pmid16547720">{{cite journal |vauthors=Sharma H, Jane MJ, Reid R |title=Chondromyxoid fibroma of the foot and ankle: 40 years' Scottish bone tumour registry experience |journal=Int Orthop |volume=30 |issue=3 |pages=205–9 |date=June 2006 |pmid=16547720 |pmc=2532097 |doi=10.1007/s00264-005-0046-y |url=}}</ref><ref name="pmid27974911">{{cite journal |vauthors=Manta L, Suciu N, Toader O, Purcărea RM, Constantin A, Popa F |title=The etiopathogenesis of uterine fibromatosis |journal=J Med Life |volume=9 |issue=1 |pages=39–45 |date=2016 |pmid=27974911 |pmc=5152611 |doi= |url=}}</ref><ref name="pmid25879625">{{cite journal |vauthors=Borahay MA, Al-Hendy A, Kilic GS, Boehning D |title=Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy |journal=Mol. Med. |volume=21 |issue= |pages=242–56 |date=April 2015 |pmid=25879625 |pmc=4503645 |doi=10.2119/molmed.2014.00053 |url=}}</ref> <ref name="pmid24678936">{{cite journal |vauthors=Wang TT, Zhang R, Wang L, Chen Y, Dong Q, Li TJ |title=Two cases of multiple ossifying fibromas in the jaws |journal=Diagn Pathol |volume=9 |issue= |pages=75 |date=March 2014 |pmid=24678936 |pmc=3974450 |doi=10.1186/1746-1596-9-75 |url=}}</ref><ref name="pmid27658992">{{cite journal |vauthors=Chen Y, Hu DY, Wang TT, Zhang R, Dong Q, Xu ZX, Wang L, Li TJ |title=CDC73 gene mutations in sporadic ossifying fibroma of the jaws |journal=Diagn Pathol |volume=11 |issue=1 |pages=91 |date=September 2016 |pmid=27658992 |pmc=5034632 |doi=10.1186/s13000-016-0532-0 |url=}}</ref><ref name="pmid23008139">{{cite journal |vauthors=Bowers LM, Cohen DM, Bhattacharyya I, Pettigrew JC, Stavropoulos MF |title=The non-ossifying fibroma: a case report and review of the literature |journal=Head Neck Pathol |volume=7 |issue=2 |pages=203–10 |date=June 2013 |pmid=23008139 |doi=10.1007/s12105-012-0399-7 |url=}}</ref> <ref name="pmid19930688">{{cite journal |vauthors=Schneider M, Zimmermann AC, Depprich RA, Kübler NR, Engers R, Naujoks CD, Handschel J |title=Desmoplastic fibroma of the mandible--review of the literature and presentation of a rare case |journal=Head Face Med |volume=5 |issue= |pages=25 |date=November 2009 |pmid=19930688 |doi=10.1186/1746-160X-5-25 |url=}}</ref><ref name="pmid23503999">{{cite journal |vauthors=Aremu AA, Oyedeji OA, Asaleye CM, Adetiloye VA |title=An elusive chest coin in an African child: a pleural fibroma's long, tortuous path to freedom |journal=Pan Afr Med J |volume=14 |issue= |pages=16 |date=2013 |pmid=23503999 |pmc=3597858 |doi=10.11604/pamj.2013.14.16.1874 |url=}}</ref> <ref name="pmid22472419">{{cite journal |vauthors=Torimitsu S, Nemoto T, Wakayama M, Okubo Y, Yokose T, Kitahara K, Ozawa T, Nakayama H, Shinozaki M, Sasai D, Ishiwatari T, Takuma K, Shibuya K |title=Literature survey on epidemiology and pathology of cardiac fibroma |journal=Eur. J. Med. Res. |volume=17 |issue= |pages=5 |date=March 2012 |pmid=22472419 |pmc=3351722 |doi=10.1186/2047-783X-17-5 |url=}}</ref> | ||
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:Hard Fibroma | :Hard Fibroma | ||
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*The ''hard fibroma'' (''fibroma durum'') consists of many fibers and a few cells, e.g. in the skin it is called ''[[dermatofibroma]]'' (''fibroma simplex'' or ''nodulus cutaneous''). | *The ''hard fibroma'' (''fibroma durum'') consists of many fibers and a few [[cells]], e.g. in the [[skin]] it is called ''[[dermatofibroma]]'' (''fibroma simplex'' or ''nodulus cutaneous''). | ||
*A special form is the ''keloid'', which derives from hyperplastic growth of scars. | *A special form is the ''[[keloid]]'', which derives from [[hyperplastic]] growth of [[scars]]. | ||
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:Soft Fibroma | :Soft Fibroma | ||
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*The ''soft fibroma'' (''fibroma molle'') or ''fibroma with a shaft'' (''acrochordon'', ''skin tag'', ''fibroma pendulans'') consist of many loosely connected cells and less fibrous tissue. | *The ''soft fibroma'' (''fibroma molle'') or ''fibroma with a shaft'' (''acrochordon'', ''skin tag'', ''fibroma pendulans'') consist of many loosely connected [[cells]] and less [[fibrous tissue]]. | ||
*They mostly appear on the neck, armpits or groin. | *They mostly appear on the [[neck]], [[armpits]] or [[groin]]. | ||
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:Other types of fibroma | :Other types of fibroma | ||
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*The ''fibroma cavernosum'' or ''angiofibroma'' | *The ''fibroma cavernosum'' or ''[[angiofibroma]]'' | ||
**It consists of many dilated vessels, it is a vasoactive tumor occurring almost exclusively in adolescent males. | **It consists of many dilated [[vessels]], it is a [[vasoactive]] [[tumor]] occurring almost exclusively in adolescent [[males]]. | ||
*The ''[[cystic | *The ''[[cystic]] fibroma'' (''fibroma cysticum'') | ||
**It has central softening or dilated lymphatic vessels. | **It has central softening or dilated [[lymphatic vessels]]. | ||
*''[[Myxofibroma]]'' | *''[[Myxofibroma]]'' | ||
**The ''myxofibroma'' (''fibroma myxomatodes'') is produced by liquefaction of the underlying soft tissue. | **The ''myxofibroma'' (''fibroma myxomatodes'') is produced by liquefaction of the underlying soft tissue. | ||
*''[[Cemento-ossifying fibroma]]'' | *''[[Cemento-ossifying fibroma]]'' | ||
**The cemento-ossifying fibroma is hard and fibrous, most frequently seen on the jaw or in the mouth, sometimes in connection with a fracture or another type of injury. | **The cemento-ossifying fibroma is hard and [[fibrous]], most frequently seen on the [[jaw]] or in the [[mouth]], sometimes in connection with a [[fracture]] or another type of [[injury]]. | ||
*Other fibromas: | *Other fibromas: | ||
**''[[Chondromyxoid fibroma]]'' | **''[[Chondromyxoid fibroma]]'' | ||
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:[[Ovarian Fibroma]] | :[[Ovarian Fibroma]] | ||
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*It appears in the sex cord-stromal tumor group of ovarian neoplasms. | *It appears in the [[sex cord-stromal tumor]] group of [[ovarian]] [[neoplasms]]. | ||
*Upon gross pathological inspection, ovary fibromas are firm and white or tan. | *Upon gross [[pathological]] inspection, ovary fibromas are firm and white or tan. | ||
*Variants with edema are especially likely to be associated with [[Meigs' syndrome]]. | *Variants with [[edema]] are especially likely to be associated with [[Meigs' syndrome]]. | ||
*On microscopic examination, there are intersecting bundles of [[spindle cells]] producing collagen. There may be thecomatous areas ([[fibrothecoma]]). | *On [[microscopic examination]], there are intersecting bundles of [[spindle cells]] producing [[collagen]]. There may be thecomatous areas ([[fibrothecoma]]). | ||
*The presence of an ovarian fibroma can cause ovarian torsion in some cases. | *The presence of an ovarian fibroma can cause [[ovarian torsion]] in some cases. | ||
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[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Up-To-Date]] | |||
[[Category:Medicine]] | [[Category:Medicine]] | ||
Latest revision as of 15:51, 23 July 2019
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Fibroma Microchapters |
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Fibroma classification On the Web |
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American Roentgen Ray Society Images of Fibroma classification |
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Risk calculators and risk factors for Fibroma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2],Simrat Sarai, M.D. [3]
Overview
There is no classification system established for fibroma. Based on the pathophysiology and location of the tumor, fibroma may be classified into hard fibroma, soft fibroma, angiofibroma, cystic fibroma, chondromyxoid fibroma, desmoplastic fibroma, nonossifying fibroma, ossifying fibroma, nuchal fibroma, collagenous fibroma, fibroma of tendon sheath, perifollicular fibroma, pleomorphic fibroma, uterine fibroma, neurofibroma, and ovarian fibroma.[1]
Classification
Based on the pathophysiology and location of the tumor fibroma may be classified into the following types, which is shown below in a tabular form:[2][3][4] [5][6][7][8] [9][10][11] [12][13] [14]
| Type of Fibroma | Features |
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References
- ↑ fibroma. Wikipedia(2015) https://en.wikipedia.org/wiki/Fibroma Accessed on February 25, 2016
- ↑ Boujoual M, Hakimi I, Kouach J, Oukabli M, Moussaoui DR, Dehayni M (2015). "Large twisted ovarian fibroma in menopausal women: a case report". Pan Afr Med J. 20: 322. doi:10.11604/pamj.2015.20.322.5998. PMC 4491469. PMID 26175813.
- ↑ Chen H, Liu Y, Shen LF, Jiang MJ, Yang ZF, Fang GP (November 2016). "Ovarian thecoma-fibroma groups: clinical and sonographic features with pathological comparison". J Ovarian Res. 9 (1): 81. doi:10.1186/s13048-016-0291-2. PMC 5120502. PMID 27876070.
- ↑ Matsuda K, Tateishi S, Akazawa Y, Kinoshita A, Yoshida S, Morisaki S, Fukushima A, Matsuwaki T, Yoshiura KI, Nakashima M (October 2016). "Rapid growth of mitotically active cellular fibroma of the ovary: a case report and review of the literature". Diagn Pathol. 11 (1): 101. doi:10.1186/s13000-016-0554-7. PMID 27770806.
- ↑ Takenaga RK, Frassica FJ, McCarthy EF (2007). "Subperiosteal chondromyxoid fibroma: a report of two cases". Iowa Orthop J. 27: 104–7. PMC 2150655. PMID 17907440.
- ↑ Sharma H, Jane MJ, Reid R (June 2006). "Chondromyxoid fibroma of the foot and ankle: 40 years' Scottish bone tumour registry experience". Int Orthop. 30 (3): 205–9. doi:10.1007/s00264-005-0046-y. PMC 2532097. PMID 16547720.
- ↑ Manta L, Suciu N, Toader O, Purcărea RM, Constantin A, Popa F (2016). "The etiopathogenesis of uterine fibromatosis". J Med Life. 9 (1): 39–45. PMC 5152611. PMID 27974911.
- ↑ Borahay MA, Al-Hendy A, Kilic GS, Boehning D (April 2015). "Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy". Mol. Med. 21: 242–56. doi:10.2119/molmed.2014.00053. PMC 4503645. PMID 25879625.
- ↑ Wang TT, Zhang R, Wang L, Chen Y, Dong Q, Li TJ (March 2014). "Two cases of multiple ossifying fibromas in the jaws". Diagn Pathol. 9: 75. doi:10.1186/1746-1596-9-75. PMC 3974450. PMID 24678936.
- ↑ Chen Y, Hu DY, Wang TT, Zhang R, Dong Q, Xu ZX, Wang L, Li TJ (September 2016). "CDC73 gene mutations in sporadic ossifying fibroma of the jaws". Diagn Pathol. 11 (1): 91. doi:10.1186/s13000-016-0532-0. PMC 5034632. PMID 27658992.
- ↑ Bowers LM, Cohen DM, Bhattacharyya I, Pettigrew JC, Stavropoulos MF (June 2013). "The non-ossifying fibroma: a case report and review of the literature". Head Neck Pathol. 7 (2): 203–10. doi:10.1007/s12105-012-0399-7. PMID 23008139.
- ↑ Schneider M, Zimmermann AC, Depprich RA, Kübler NR, Engers R, Naujoks CD, Handschel J (November 2009). "Desmoplastic fibroma of the mandible--review of the literature and presentation of a rare case". Head Face Med. 5: 25. doi:10.1186/1746-160X-5-25. PMID 19930688.
- ↑ Aremu AA, Oyedeji OA, Asaleye CM, Adetiloye VA (2013). "An elusive chest coin in an African child: a pleural fibroma's long, tortuous path to freedom". Pan Afr Med J. 14: 16. doi:10.11604/pamj.2013.14.16.1874. PMC 3597858. PMID 23503999.
- ↑ Torimitsu S, Nemoto T, Wakayama M, Okubo Y, Yokose T, Kitahara K, Ozawa T, Nakayama H, Shinozaki M, Sasai D, Ishiwatari T, Takuma K, Shibuya K (March 2012). "Literature survey on epidemiology and pathology of cardiac fibroma". Eur. J. Med. Res. 17: 5. doi:10.1186/2047-783X-17-5. PMC 3351722. PMID 22472419.