Ewing's sarcoma staging: Difference between revisions
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__NOTOC__ | |||
{{Ewing's sarcoma}} | {{Ewing's sarcoma}} | ||
{{CMG}};{{AE}} {{PSK}};'''Assistant Editor(s)-In-Chief:''' {{MJM}} | |||
==Overview== | ==Overview== | ||
AJCC staging system is used for staging of Ewing's sarcoma. | |||
==Ewing's sarcoma staging== | |||
*Ewing sarcoma is classified accordig to AJCC staging system shown in table below.<ref>{{cite book | last = Edge | first = Stephen | title = AJCC cancer staging manual | publisher = Springer | location = New York | year = 2010 | isbn = 978-0-387-88440-0 }}</ref> | |||
{| class="wikitable" | |||
|+ | |||
| colspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" ! + |'''Primary tumor (T)''' | |||
|- | |||
| rowspan="2" style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Stage''' | |||
| colspan="3" style="background: #DCDCDC; padding: 5px; text-align: left;" |'''Finding''' | |||
|- | |||
|style="background: #DCDCDC; padding: 5px; text-align: left;" |'''Spine''' | |||
|style="background: #DCDCDC; padding: 5px; text-align: left;" |'''Pelvis''' | |||
|style="background: #DCDCDC; padding: 5px; text-align: left;" |'''Appendicular skeleton, trunk, skull, and facial bones''' | |||
|- | |||
|'''Tx''' | |||
| | |||
* Cannot be assessed | |||
| | |||
* Cannot be assessed | |||
| | |||
* Cannot be assessed | |||
|- | |||
| |'''T0''' | |||
| | |||
* No evidence of primary [[tumor]] | |||
| | |||
* No evidence of primary [[tumor]] | |||
| | |||
* No evidence of primary [[tumor]] | |||
|- | |||
|'''T1''' | |||
| | |||
* Confined to one [[vertebral]] segment or two adjacent [[vertebral]] segments | |||
| | |||
* Confined to one [[pelvic]] segment with no extraosseous extension | |||
| | |||
* [[Tumor]] ≤8 cm in greatest dimension | |||
* | |||
|- | |||
|'''T2''' | |||
| | |||
* Confined to three adjacent [[vertebral]] segments | |||
| | |||
* Confined to one [[pelvic]] segment with extraosseous extension or two segments without extraosseous extension | |||
| | |||
* [[Tumor]] >8 cm in greatest dimension | |||
* | |||
* | |||
|- | |||
|'''T3''' | |||
| | |||
* Confined to four or more adjacent [[vertebral]] segments, or any nonadjacent [[vertebral]] segments | |||
| | |||
* Spanning two [[pelvic]] segments with extraosseous extension | |||
| | |||
* Discontinuous [[tumors]] in the primary [[bone]] site | |||
* | |||
== | * | ||
|- | |||
* | |'''T4''' | ||
** | | | ||
**Stage | * Extension into the [[spinal canal]] or great [[vessels]] | ||
| | |||
* Spanning three [[pelvic]] segments or crossing the [[sacroiliac joint]] | |||
|_ | |||
* | |||
* | |||
|- | |||
|+ | |||
! colspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Regional lymph nodes (N)''' | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Stage''' | |||
| colspan="3" style="background: #DCDCDC; padding: 5px; text-align: left;" |'''Finding''' | |||
|- | |||
!Nx | |||
| colspan="3" | | |||
* cannot be assessed | |||
* | |||
|- | |||
!N0 | |||
| colspan="3" | | |||
* No regional [[lymph node]] [[metastasis]] | |||
* | |||
|- | |||
!N1 | |||
| colspan="3" | | |||
* Regional [[lymph node]] [[metastasis]] | |||
|- | |||
|+ | |||
! colspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" + |Distant metastasis (M) | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Stage''' | |||
| colspan="3" style="background: #DCDCDC; padding: 5px; text-align: left;" |'''Finding''' | |||
|- | |||
!M0 | |||
| colspan="3" | | |||
* No distant [[metastasis]] | |||
* | |||
|- | |||
!M1 | |||
| colspan="3" | | |||
* Distant [[metastasis]] | |||
* | |||
* | |||
|- | |||
!M1a | |||
| colspan="3" | | |||
* Distant [[metastasis]] to [[lung]] | |||
* | |||
* | |||
|- | |||
!M1b | |||
| colspan="3" | | |||
* Distant [[metastasis]] to [[bone]] or other distant sites | |||
* | |||
* | |||
|- | |||
| colspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Histologic grade (G)''' | |||
|- | |||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |'''Stage''' | |||
| colspan="3" style="background: #DCDCDC; padding: 5px; text-align: left;" |'''Finding''' | |||
|- | |||
!Gx | |||
| colspan="3" | | |||
* cannot be assessed | |||
* | |||
|- | |||
!G1 | |||
| colspan="3" | | |||
* Low grade | |||
* | |||
|- | |||
!G2 | |||
| colspan="3" | | |||
* High grade (moderately differentiated) | |||
* | |||
|- | |||
!G3 | |||
| colspan="3" | | |||
* High grade (poorly differentiated) | |||
|- | |||
|- | |||
!G4 | |||
| colspan="3" | | |||
* Undifferentiated | |||
|- | |||
|} | |||
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center | |||
|+'''''Anatomic Stage/Prognostic Groups''''' | |||
! style="background: #4479BA; width: 120px;" | {{fontcolor|#FFF|Stage}} | |||
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|T}} | |||
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|N}} | |||
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|M}} | |||
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|G}} | |||
|- | |||
| colspan="5" style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" align="center" | '''Ewing's Sarcoma''' | |||
|- | |||
! style="background: #DCDCDC;" |IA | |||
! style="background: #F5F5F5;" |T1 | |||
! style="background: #F5F5F5;" |N0 | |||
! style="background: #F5F5F5;" |M0 | |||
! style="background: #F5F5F5;" |G1,2, GX | |||
|- | |||
! rowspan="2" style="background: #DCDCDC;" |IB | |||
! style="background: #F5F5F5;" |T2 | |||
! style="background: #F5F5F5;" |N0 | |||
! style="background: #F5F5F5;" |M0 | |||
! style="background: #F5F5F5;" |G1,2, GX | |||
|- | |||
! style="background: #F5F5F5;" |T3 | |||
! style="background: #F5F5F5;" |N0 | |||
! style="background: #F5F5F5;" |M0 | |||
! style="background: #F5F5F5;" |G1,2, Gx | |||
|- | |||
! style="background: #DCDCDC;" |IIA | |||
! style="background: #F5F5F5;" |T1 | |||
! style="background: #F5F5F5;" |N0 | |||
! style="background: #F5F5F5;" |M0 | |||
! style="background: #F5F5F5;" |G3,4 | |||
|- | |||
! style="background: #DCDCDC;" |IIB | |||
! style="background: #F5F5F5;" |T2 | |||
! style="background: #F5F5F5;" |N0 | |||
! style="background: #F5F5F5;" |M0 | |||
! style="background: #F5F5F5;" |G3, 4 | |||
|- | |||
! style="background: #DCDCDC;" |III | |||
! style="background: #F5F5F5;" |T3 | |||
! style="background: #F5F5F5;" |N0 | |||
! style="background: #F5F5F5;" |M0 | |||
! style="background: #F5F5F5;" |G3,4 | |||
|- | |||
! style="background: #DCDCDC;" |IVA | |||
! style="background: #F5F5F5;" |Any T | |||
! style="background: #F5F5F5;" |N0 | |||
! style="background: #F5F5F5;" |M1a | |||
! style="background: #F5F5F5;" |Any G | |||
|- | |||
! rowspan="2" style="background: #DCDCDC;" |IVB | |||
! rowspan="2" style="background: #F5F5F5;" |Any T | |||
! style="background: #F5F5F5;" |Any N | |||
! style="background: #F5F5F5;" |Any M | |||
! style="background: #F5F5F5;" |Any G | |||
|- | |||
! style="background: #F5F5F5;" |N1 | |||
! style="background: #F5F5F5;" |M1b | |||
! style="background: #F5F5F5;" |Any G | |||
|} | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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Latest revision as of 14:55, 28 October 2019
Ewing's sarcoma Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Ewing's sarcoma staging On the Web |
American Roentgen Ray Society Images of Ewing's sarcoma staging |
Risk calculators and risk factors for Ewing's sarcoma staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2];Assistant Editor(s)-In-Chief: Michael Maddaleni, B.S.
Overview
AJCC staging system is used for staging of Ewing's sarcoma.
Ewing's sarcoma staging
- Ewing sarcoma is classified accordig to AJCC staging system shown in table below.[1]
Primary tumor (T) | |||
Stage | Finding | ||
Spine | Pelvis | Appendicular skeleton, trunk, skull, and facial bones | |
Tx |
|
|
|
T0 |
|
|
|
T1 |
|
| |
T2 |
|
|
|
T3 |
|
| |
T4 |
|
|
_
|
Regional lymph nodes (N) | |||
---|---|---|---|
Stage | Finding | ||
Nx |
| ||
N0 |
| ||
N1 |
| ||
Distant metastasis (M) | |||
Stage | Finding | ||
M0 |
| ||
M1 |
| ||
M1a |
| ||
M1b |
| ||
Histologic grade (G) | |||
Stage | Finding | ||
Gx |
| ||
G1 |
| ||
G2 |
| ||
G3 |
| ||
G4 |
|
Stage | T | N | M | G |
---|---|---|---|---|
Ewing's Sarcoma | ||||
IA | T1 | N0 | M0 | G1,2, GX |
IB | T2 | N0 | M0 | G1,2, GX |
T3 | N0 | M0 | G1,2, Gx | |
IIA | T1 | N0 | M0 | G3,4 |
IIB | T2 | N0 | M0 | G3, 4 |
III | T3 | N0 | M0 | G3,4 |
IVA | Any T | N0 | M1a | Any G |
IVB | Any T | Any N | Any M | Any G |
N1 | M1b | Any G |
References
- ↑ Edge, Stephen (2010). AJCC cancer staging manual. New York: Springer. ISBN 978-0-387-88440-0.