Etidocaine: Difference between revisions

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{{Drugbox|
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 461097787
| IUPAC_name = ''N''-(2,6-dimethylphenyl)-<br />2-(ethyl(propyl)amino)butanamide
| IUPAC_name = ''N''-(2,6-dimethylphenyl)-<br />2-(ethyl(propyl)amino)butanamide
| image = Etidocaine.png
| image = Etidocaine.png
| ATC_prefix=N01
 
| ATC_suffix=BB07
<!--Clinical data-->
| PubChem=37497
| tradename = Duranest
| DrugBank=n/a
| Drugs.com = {{drugs.com|CONS|etidocaine}}
| CAS_number = 36637-18-0
| MedlinePlus = a603026
| C = 17 | H = 28 | N = 2 | O = 1
| pregnancy_AU = B1
| molecular_weight = 276.42 g/mol
| pregnancy_US = B
| legal_US = Rx-only
| routes_of_administration = [[Parenteral]]
 
<!--Pharmacokinetic data-->
| bioavailability = n/a
| bioavailability = n/a
| metabolism = [[Liver|Hepatic]]
| metabolism = [[Liver|Hepatic]]
| elimination_half-life = 2.5 hours
| elimination_half-life = 2.5 hours
| excretion = [[Kidney|Renal]]
| excretion = [[Kidney|Renal]]
| pregnancy_AU = B1
 
| pregnancy_US = B
<!--Identifiers-->
| legal_US = Rx-only
| CAS_number_Ref = {{cascite|changed|??}}
| routes_of_administration = [[Parenteral]]
| CAS_number = 36637-18-0
| ATC_prefix = N01
| ATC_suffix = BB07
| PubChem = 37497
| IUPHAR_ligand = 2621
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
| DrugBank = DB08987
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 34400
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = I6CQM0F31V
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D04095
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 4904
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 492
 
<!--Chemical data-->
| C=17 | H=28 | N=2 | O=1
| molecular_weight = 276.42 g/mol
| smiles = O=C(Nc1c(C)cccc1C)C(CC)N(CC)CCC
| InChI = 1/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20)
| InChIKey = VTUSIVBDOCDNHS-UHFFFAOYAV
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = VTUSIVBDOCDNHS-UHFFFAOYSA-N
}}
}}
'''Etidocaine''', marketed under the trade name '''Duranest''', is a [[local anesthetic]] given by [[Injection (medicine)|injection]] during [[surgery|surgical procedures]] and [[childbirth|labor and delivery]].
'''Etidocaine''', marketed under the trade name '''Duranest''', is a [[local anesthetic]] given by [[Injection (medicine)|injection]] during [[surgery|surgical procedures]] and [[childbirth|labor and delivery]]. Etidocaine has a long duration of activity, and the main disadvantage of using during dentistry is increased bleeding during surgery.<ref>{{cite pmid|1308373}}</ref>
 
== References ==
{{reflist}}
 
== External links ==
* [http://www.rxlist.com/duranest-drug.htm Duranest] (RxList)


{{Local anesthetics}}
{{Local anesthetics}}


[[Category:Local anesthetics]]
[[Category:Local anesthetics]]
[[Category:Anilides]]


{{pharma-stub}}


[[fr:Étidocaïne]]
{{nervous-system-drug-stub}}

Revision as of 14:46, 13 April 2015

Etidocaine
Clinical data
Trade namesDuranest
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa603026
Pregnancy
category
  • AU: B1
  • US: B (No risk in non-human studies)
Routes of
administration		Parenteral
ATC code
Legal status
Legal status
Pharmacokinetic data
Bioavailabilityn/a
MetabolismHepatic
Elimination half-life2.5 hours
ExcretionRenal
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC17H28N2O
Molar mass276.42 g/mol
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Etidocaine, marketed under the trade name Duranest, is a local anesthetic given by injection during surgical procedures and labor and delivery. Etidocaine has a long duration of activity, and the main disadvantage of using during dentistry is increased bleeding during surgery.[1]

References

  1. ↑ PMID 1308373 (PMID 1308373)
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External links


Template:Nervous-system-drug-stub

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