Eosinophilic pneumonia natural history, complications, and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Priyamvada Singh, M.D. [2]
Overview
Natural History
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3]. Common complications of [disease name] include [complication 1], [complication 2], and [complication 3]. Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Complications
Chronic prednisone is associated with many side effects, including increased infections, weakened bones, stomach ulcers, and changes in appearance.[3]
Relapse
RF; Extrapulmonary organ failure or shock is exceptional, and only a couple of lethal cases have been reported. 52,91
Prognosis
- some people with CEP require lifelong therapy.
- response to corticosteroid treatment is dramatic and treatment always leads to complete resolution, pulmonary function tests return to normal after recovery from the illness [8]. The pleural effusions may resolve more slowly than the pulmonary parenchymal opacities [9].
- relapses of ICEP are observed in up to 50% of patients and is usually associated with resumption of cigarette smoking after initial cessation [14,18-20]. [3]
- These relapses occur while tapering the dose of corticosteroids or after weaning.