Eosinophilic pneumonia epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
* IAEP occurs acutely in previously healthy young adults, with a mean age of approximately 30 years, and with male predominance.48–53 Two-thirds of patients are smokers, but there is usually no history of asthma. | |||
* The disease can be triggered by various respiratory exposures, especially a recent initiation of tobacco smoking (as in military or new college student settings52). | |||
* A change in smoking habits,53,54 smoking large quantities of cigarettes (or cigars), reintroduction to smoking (“rechallenge”),50,53–62 or even short-term passive smoking54,63 also can trigger IAEP. A variety of nonspecific environmental inhaled contaminants also have been demonstrated to induce IAEP.1 | |||
* Whether this condition should be termed “idiopathic” acute eosinophilic pneumonia in cases clearly related to tobacco smoking or other exposures is debatable.4 | |||
* The incidence of CEP in an Icelandic registry was 0.23 cases/100,000 population per year between 1990 and 2004 [3]. | * The incidence of CEP in an Icelandic registry was 0.23 cases/100,000 population per year between 1990 and 2004 [3]. | ||
* In registries of interstitial lung disease (ILD) in Europe, CEP accounted for 0 to 2.5 percent of cases of ILD [4]. | * In registries of interstitial lung disease (ILD) in Europe, CEP accounted for 0 to 2.5 percent of cases of ILD [4]. | ||
Revision as of 20:19, 9 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Epidemiology and Demographics
- IAEP occurs acutely in previously healthy young adults, with a mean age of approximately 30 years, and with male predominance.48–53 Two-thirds of patients are smokers, but there is usually no history of asthma.
- The disease can be triggered by various respiratory exposures, especially a recent initiation of tobacco smoking (as in military or new college student settings52).
- A change in smoking habits,53,54 smoking large quantities of cigarettes (or cigars), reintroduction to smoking (“rechallenge”),50,53–62 or even short-term passive smoking54,63 also can trigger IAEP. A variety of nonspecific environmental inhaled contaminants also have been demonstrated to induce IAEP.1
- Whether this condition should be termed “idiopathic” acute eosinophilic pneumonia in cases clearly related to tobacco smoking or other exposures is debatable.4
- The incidence of CEP in an Icelandic registry was 0.23 cases/100,000 population per year between 1990 and 2004 [3].
- In registries of interstitial lung disease (ILD) in Europe, CEP accounted for 0 to 2.5 percent of cases of ILD [4].
- A majority of patients are nonsmokers.
- ICEP is a rare disorder. Its exact prevalence remains unknown.
- ICEP has been reported to contribute to 0– 2.5% of cases included in different registries of interstitial lung diseases [1].
- ICEP may affect every age group but is extremely rare in childhood [2-5].
- It is twice as frequent in women as in men [2,3,6,7].
- One third to one half of the ICEP patients have a history of asthma [7-12];
- less than 10% are active smokers [2,3,7].
- It has recently been reported that ICEP may be primed by radiation therapy for breast cancer [13].