Empyema

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Empyema
ICD-10 J86
ICD-9 510
DiseasesDB 4200
MedlinePlus 000123
MeSH D016724

Empyema Microchapters

Patient Information

Overview

Classification

Subdural empyema
Pleural empyema

Differential Diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Pyothorax

Overview

An empyema is a collection of pus within the pleural cavity. It must be differentiated from an abscess, which is a collection of pus in a newly formed cavity. Most empyemas arise from an infection within the lung (pneumonia), often associated with parapneumonic effusions.

There are 3 stages: exudative, fibrinopurulent and organizing. In the exudative stage, the pus accumulates. This is followed by the fibrinopurulent stage in which there is loculation of the pleural fluid (the creation of grapelike pus pockets). In the final organizing stage, scarring of the pleural space may lead to lung entrapment.

Pleural space empyema

Symptoms

Symptoms of empyema may vary in severity. Typical symptoms include: fever, chest pain or discomfort, cough, sweating and shortness of breath.

Clubbing of the fingernails may be present. There is a dull percussion note and reduced breath sounds on the affected side of the chest. Other diagnostic tools include chest x-ray, CT scan, and Ultrasonography.

Diagnosis

Diagnosis is confirmed by thoracentesis; frank pus may be aspirated from the pleural space. The pleural fluid typically has a low pH (<7.20), low glucose (<60 mg/dL), and contains infectious organisms.

CT chest showing large right sided hydropneumothorax from pleural empyema. Arrows A: air, B: fluid

Treatment

Definitive treatment for empyema entails drainage of the infected pleural fluid. A chest tube may be inserted, often using ultrasound guidance. Intravenous antibiotics are given. If this is insufficient, surgical debridement of the pleural space may be required.


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